Assessment of Executive Functions in Methamphetamineaddicted Individuals: Emphasis on Duration of Addiction and Abstinence

Journal Title: Basic and Clinical Neuroscience - Year 2017, Vol 8, Issue 2

Abstract

Introduction: Several studies have conducted on impairments of executive functions in individuals with methamphetamine addiction; however, only a few have investigated the relationship between executive functions and duration of addiction or abstinence. This study was designed to assess the executive functions in methamphetamine-addicted individuals in relation to the duration of addiction or abstinence. Methods: A total of 161 subjects aged between 20 and 45 years were categorized into three subgroups: currently abusing (n = 41), abstinent (n = 60), and control healthy individuals (n = 60). A battery of standardized executive function tasks, including Stroop test, Wisconsin Card Sorting test, and Tower of London task, were administered. Data were analyzed using Pearson correlation coefficient, analysis of variance, and post hoc Bonferroni test with SPSS16.0. Results: Methamphetamine-addicted and abstinent subjects performed worse than the controls. Methamphetamine-abstinent subjects performed better than the currently methamphetamine abusers in most executive functions. Duration of addiction and abstinence were correlated with executive dysfunctions. Conclusion: This study revealed that although executive functions may be improved by protracted abstinence, executive dysfunctions are not completely relieved, and specific attention to planning and implementation of intervention programs are necessary.

Authors and Affiliations

Majid Farhadian, Malahat Akbarfahimi, Peyman Hassani Abharian, Seyedeh Golaleh Hosseini, Susan Shokri

Keywords

Related Articles

Effects of Hydroalcoholic Extract of Soy on Learning, Memory and Synaptic Plasticity Deficits Induced by Seizure in Ovariectomized Rats

Introduction: Previous studies have shown that seizure can induce cognitive impairment. On the other hand, soy phytoestrogens, which are mainly found in soybean (Glycine max (L.) Merr.), have beneficial effects on the ne...

Response of the Pre-oriented Goal-directed Attention to Usual and Unusual Distractors: A Preliminary Study

Introduction: In this study, we investigated the distraction power of the unusual and usual images on the attention of 20 healthy primary school children. Methods: Our study was different from previous ones in that the...

Generating the Visual Biofeedback Signals Applicable to Reduction of Wrist Spasticity: A Pilot Study on Stroke Patients

Introduction: Application of biofeedback techniques in rehabilitation has turned into an exciting research area during the recent decade. Providing an appropriate visual or auditory biofeedback signal is the most critica...

Introducing Genes With Significant Role in Migraine: An Interactomic Approach

Introduction: Migraine is a severe kind of headache with the chance hereditary of 50%. Molecular studies can promote understanding of migraine pathophysiology. One of which is bioinformatics approach that could provide a...

Introducing Transthyretin as a Differentially Expressed Protein in Washing Subtype of Obsessive-Compulsive Disorder

Introduction: Obsessive-Compulsive Disorder (OCD) as one of the important mental problems is valuable topic for proteomic research studies to better understand the underlying mechanisms of this disorder. Methods: In thi...

Download PDF file
  • EP ID EP264678
  • DOI 10.18869/nirp.bcn.8.2.147
  • Views 89
  • Downloads 0

How To Cite

Majid Farhadian, Malahat Akbarfahimi, Peyman Hassani Abharian, Seyedeh Golaleh Hosseini, Susan Shokri (2017). Assessment of Executive Functions in Methamphetamineaddicted Individuals: Emphasis on Duration of Addiction and Abstinence. Basic and Clinical Neuroscience, 8(2), -. https://europub.co.uk/articles/-A-264678