Assessment of Improvement in Feeding Behavior and Co Morbid Psychiatric Disorders in Morphine Addiction Period in Socialized Male Rats
Journal Title: International Neuropsychiatric Disease Journal - Year 2016, Vol 8, Issue 1
Abstract
Introduction: In previous studies, other function of adult hippocampal neurogenesis besides memory and learning has not been studied. The aim of this study is to discover other function of hippocampal neurogenesis, especially in addiction period. Materials and Methods: In this experiment 48 male Sprague-Dawley were randomly divided in four groups: 1) socialized 2) isolated 3) addicted socialized rats 4) addicted isolated rats. At the end of experiments short term memory, feeding behavior, blood glucose, zinc, anxiety level and neurogenesis were assessed. Results: Short term memory was impaired in addicted isolated rats compared to addicted socialized rats. Food consumption increased in addicted social rats compared to addicted isolated rats. Level of blood glucose increased in addicted socialized rats compared to addicted isolated rats. Anxiety level increased in addicted isolated rats compared to addicted socialized rats. Neurogenesis decreased in addicted isolated rats compared to addicted socialized rats. Zinc was elevated in addicted isolated rats compared to addicted socialized rats. Conclusion: Feeding behavior can be regulated by adult hippocampal neurogenesis in addiction period, and socialization improves it. Also along with these positive effects co morbid psychiatric disorder such as an anxiety improves in addiction period.
Authors and Affiliations
Morteza Karimian, Hamidreza Famitafreshi, Fatemeh Attari
Keywords
Related Articles
- EP ID EP241710
- DOI 10.9734/INDJ/2016/27633
- Views 126
- Downloads 0
Brain-Derived Neurotrophic Factor, Copper, Zinc and High Density Lipoprotein (HDL) in Patients with Dementia
The levels of BDNF, copper, zinc and common blood tests of two different groups of patients were considered: those with dementia syndrome and healthy older people. It would be premature to conclude that these indicators,...
Neuropsychological Deficits in Children with Epilepsy in Ghana: A Study at Korle-Bu Teaching Hospital
Epilepsy may be associated with a wide range of neuropsychological deficits. The study examined the neuropsychological deficits (language skills, attention skills and executive functioning) associated with epileptic chil...
Examining the Impact of Patient-Reported Hope for Improvement and Patient Satisfaction with Clinician/Treatment on the Outcome of Major Depressive Disorder Treatment
Aims: This analysis aims at examining if patient-reported variables such as hope for improvement and patient satisfaction with clinician/treatment could influence the outcome major depressive disorder (MDD) treatment, na...
Mental and Social Health Atlas: An Update, Ministry of Health, Saudi Arabia, 2015
Background: Mental health (MH) is an extremely integral component of health and accordingly there is “no health without mental health’’. Objective: Based on the concept of World Health Organization (WHO) Mental Health D...
Treatment of Primary Headaches in Paediatric Age: A Comprehensive Review
Primary headaches have a high prevalence in paediatric age and may pose a high strain on the quality of life of young patients. Adequate care involves a patient-by-patient approach, and this generally relies both on bio-...