Assessment of Incidence of Superbugs and Antibiotic Resistance in Orthopaedics, A Cross-Sectional Study
Journal Title: Journal of Pakistan Orthopaedic Association - Year 2023, Vol 35, Issue 04
Abstract
Objectives: Due to the presence of metallic implants, orthopedic surgeries are at increased risk of microbiological contamination and infection. Such infections require aggressive and prolonged use of antimicrobial therapy. The objective of our study is to determine the frequency of growth in cultures and identify patterns of new antibiotic resistance from culture growth of infected implant patients. Methods: Total 188 patients were included in this study which was conducted in Liaquat National Hospital from July 2022 till July 2023. Suspected infections were confirmed biochemically when ESR ?30mm/hour or CRP ?10 mg/dl. Such patients underwent routine surgeries for infection eradication as per routine orthopaedic guidelines. Appropriate body tissue specimens were sampled for culture and sensitivity. Descriptive statistics were calculated. Results: There were 64.4% male and 35.6% female patients. Mean age was 43.61±14.21 years. Mean ESR and CRP was 63.89±34.92 mm/hour and 6.11±4.54 mg/dl respectively. In 23.9% previous surgical procedure was ORIF. In our study, 87.8% of patients were found with culture growth while most common culture bacterium was MRSA found among 40.6% patients. Most sensitive antibiotic was Vancomycin (67.3%). 13.2% of patients showed no growth indicating significant covert or indolent bacteria. Conclusion: Culture growth was observed in 87.8% patients with MRSA being the most common organism. Vancomycin was found as most sensitive antibiotic.
Authors and Affiliations
Twahir Kalekhan Dina1, Sobia Aziz2, Aqsa Aman Katto3, Zaki Idrees4, Syed Shahid Noor5
Keywords
Related Articles
- EP ID EP740839
- DOI -
- Views 24
- Downloads 0
Motorbike Spoke-Wheel Injuries of the lower limb treated with Fascio-Cutaneous Sural Artery Flap at a Tertiary Care Hospital
Objective: To determine the efficacy of reverse fascio-cutaneous sural artery flap in the treatment of heel pad injuries due motorbike spoke-wheel trauma. Methods: This descriptive study was conducted in Department of...
Isolated Congenital unilateral Aplasia of Patella with contralateral Hypoplasia of Patella-A Case Report.
Congenital absence of patella(aplasia) or small size patella(hypoplasia) is very rare and usually associated with other anomalies like Nail Patella Syndrome, Ischiopatellar dysplasia and Turner-Kiesser syndrome. This con...
Can Post Graduate Trainees benefit from Microteaching?
Training of post graduates is a fast changing field all over the world. Microteaching has been a time tested technique since long but its use has decreased over time especially in medical field. It is a group activity fo...
COVID-19 and Practice of Orthopaedic Surgery: Pakistan Perspective.
The Global pandemic of COVID-19 has affected the health care system worldwide. Hospitals in Pakistan are getting overcrowded with COVID-19 patients and healthcare workers are getting infected with virus in increased numb...
Management of Infected Non Union Tibial Shaft by Ilizarov Method
To asses the out come of the management of infected non union of tibial shaft by Ilizarov method. Patients and Methods: This prospective study was conducted at department of orthopedic CMC Larkana and GMMMC Sukkur fro...