Assessment of Insulin Resistance, Serum Adiponectin and Ferritin Levels in HCC Patients Before and After Radiofrequency Ablation
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 5
Abstract
Hepatitis C virus (HCV) is a major cause of chronic hepatitis, hepatocellular carcinoma (HCC), and recently HCV has been identified as a cause of insulin resistance (IR). Recent studies have found that HCV-associated IR causes hepato-carcinogenesis and proliferation of HCC where IR may synergize with viral hepatitis in HCC development. The aim of the present work was to study IR, serum alphafetoprotein (AFP); adiponectin and ferritin levels in HCV-positive cirrhotic patients with and without HCC. Also, these markers were assessed in early stage HCC patients after successful treatment with radiofrequency ablation (RFA). Moreover, liver stiffness was measured using acoustic radiation force impulse imaging (ARFI) in all studied patients.
Authors and Affiliations
Fathallah Sidkey Mohamed
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