Assessment of Interleukin (8) in Type 2 Diabetes Mellitus
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 72, Issue 4
Abstract
<strong>Background: </strong>Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. The chronic hyperglycemia of diabetes is associated with long- term damage, dysfunction, and failure of different organs, especially the eyes, kidneys, nerves, heart, and blood vessels. Type 2 diabetes (T2D) is characterized by a condition of systemic low-grade inflammation. IL-8 is an important member of the chemokine family of proinflammatory chemotactic cytokines. IL-8 was initially characterized as a potent chemoattractant of neutrophils and was later shown to also activate neutrophils. IL-8 is also known to be a potent promoter of angiogenesis. <strong>Objective: </strong>It was the Assessment of Interleukin (8) in Type 2 Diabetes Mellitus. <strong>Patients and Methods: </strong>Serum IL 8 level in Type 2 Diabetes Mellitus. 30 patients compared to 30 normal individuals were included in this study. <strong>Results: </strong>There was a highly statistical significant difference between all patients and control groups as regard serum IL 8 level (mean of serum IL 8 in patients and control groups were 69.9 ± 20.5 and 5.4 ± 3.3 respectively, p= < 0.001). <strong>Conclusion: </strong>Type 2 diabetes mellitus patients showed marked elevation of circulating IL-8 levels which identify subjects with worse inflammatory state and metabolic control and therefore it may be used as a marker for the rate of development of diabeteic complications.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP584150
- DOI 10.12816/ejhm.2018.9298
- Views 101
- Downloads 0
Knowledge, Attitude and Practice Related to Health Impact of Performance-Enhancing Drugs among the Male Students in Qassim University
<span>Background: </span><span>Performance-Enhancing Drugs </span><span>( PEDs ) are used by young adults to enhance physical performance and appearance. There are many medical problems associated with </span><span>Perfo...
Effect of Chest Physical Therapy Modalities on Oxygen Saturation and Partial Pressure of Arterial Oxygen in Mechanically Ventilated Patients
<strong>Background: </strong>Chest physical therapy plays an important role in increasing Pao2 and SaO2 among ICU patients which is considered as a good indicator for the general improvement of the patient besides decrea...
Knowledge, Attitude and Practices About Pneumococcal Infection among Algerian Hajj Pilgrims
<strong>Background: </strong>Hajj attendance increases the risk of respiratory infections including pneumonia. Pneumococcal infections are caused by Streptococcus pneumonia, a gram-positive, catalase-negative organism no...
Atherosclerosis: Pathophysiology and Management
Background: Atherothrombotic cardiovascular disease is currently the leading cause of morbidity, mortality and cost burden in the medical community. New studies have found atherosclerosis to be predominantly an inflammat...
Conventional Hemorrhoidectomy versus Ligasure Hemorrhoidectomy: A Comparative Study
<strong>Background: </strong>Hemorrhoidal disease is one of the most common anorectal diseases and surgical hemorrhoidectomy remains one of the most common operations in general surgery. Milligan-Morgan Described the con...