Assessment of Lipid profile and Glycated Hemoglobin in Newly Diagnosed type 2 Diabetes Mellitus in Rural Population of Indore, M.P, India
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 2
Abstract
Prevalence of dyslipidemia in type 2 diabetes mellitus patients is higher and positively correlated with BMI. The present study was designed to assess the glycemic control and lipid profile in newly diagnosed type 2 diabetes mellitus in rural population of Indore. The study was conducted on 100 newly diagnosed type 2 diabetes mellitus patients ( male- 70, female- 30) mean age 45.50 ±4.8 years and the control groups consisted of 80 healthy individuals (male-60, female-20) mean age 42.35 ± 2.4 years. Analysis of various biochemical parameters was performed by standard kit methods. Fasting and postprandial blood sugar, HbA1c and lipid profile were compared in type 2 daibetics and control subjects and also compared according to BMI in diabetic patients. Statistical analysis was done by unpaired t-test. The fasting and postprandial blood sugar, total cholesterol, triglycerides, LDL, VLDL, HbA1c were significantly increased and HDL was significantly decreased in diabetics compared to control subjects (p< 0.001). All the lipid parameters were significantly increased in group 2 except HDL which was significantly decreased compared to group 1. Both males and females showed increased incidence of dyslipidemia /hyperlipidemia with increasing BMI. Reduction in BMI and early detection of dyslipidemia and its treatment are key factors to achieve good glycemic control to prevent microvascular and macrovascular complications in type 2 diabetes mellitus patients.. Keywords: BMI (body mass index), Dyslipidemia, Glycated hemoglobin, Lipid profile
Authors and Affiliations
Roshan Alam, Mohammad Aleem, Saba Khan, Shah Mohammad Abbas Waseem
Keywords
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