Assessment of Methaemoglobin and Carboxyhaemoglobin Levels among Pregnant Women Infected with Hepatitis B Virus
Journal Title: Biotechnology Journal International - Year 2016, Vol 10, Issue 4
Abstract
Aims: The goal of this research is to determine plasma levels of MetHb and COHb in pregnant women with hepatitis B, which might enhance oxidative stress and hypoxemic condition of this state if it is not ameliorated on time. Study Design: Prospective case-control study. Place and Duration of Study: Antenatal clinic at Primary Health Centres, Sagamu, Ogun State, Nigeria between February, 2015 and August, 2015. Methodology: Blood levels of MetHb, COHb and bilirubin were determined in ninety four (94) participants (aged 18-40 years), divided into three groups: 33 pregnant women infected with hepatitis B virus, 30 apparently healthy pregnant women and 31 age matched non pregnant women apparently healthy controls. Blood levels of MetHb, COHb and bilirubin were determined using standard spectrophotometric method. Results: There was progressive increase and decrease in mean blood levels of (TBil, and MetHb) and mean blood levels of COHb respectively from controls through pregnant subjects with HBV. PCV and DBil had no specific pattern of differences across the groups. Conclusion: This study showed a slight increase in blood levels of MetHb in pregnant women with hepatitis B and apparently healthy pregnant women compared to non-pregnant controls, which might enhance oxidative stress and hypoxemic condition of this state. It would also be helpful to incorporate MetHb screening as routine tests for better management of pregnant women especially with HBV.
Authors and Affiliations
Adedeji David Atere, Franklin Kayode Ayenogun, Bolaji David Akinbo, Adaobi Mary-Joy Okafor, Kelvin Ifeanyichukwu Egbuchulem
Keywords
Related Articles
- EP ID EP237700
- DOI 10.9734/BBJ/2016/21880
- Views 86
- Downloads 0
Characteristics of Penicillin G Acylase Immobilized onto Iron Oxide Nanoparticles
Penicillin G acylase was immobilized onto iron oxide nanoparticles coated with polyethyleneimine and then cross linked with glutaraldehyde solution. The FTIR spectrum of immobilized enzyme showed peak at 1648cm-1 which c...
Plant Regeneration via Somatic Embryogenesis in an Ethnomedicinal Plant Senna alata (L.) Roxb.
Aim: To study the effect of various plant growth regulators (PGRs) for induction of somatic embryogenesis and plantlet regeneration from cotyledon and leaflet explants in Senna alata (L.) Roxb. (Syn. Cassia alata) an imp...
Analysis of Bio-gas Production from Cow Dung by Indigenous Microbial Consortia
The study analyzed quantitatively and qualitatively the biogas produced from cowdung by indigenous microbial consortia. Four 20L bioreactors were used for the study. The bioreactors were constructed to imitate the fixed...
Attempt to Establish Direct Gene Transformation System to Seeds of Sweet Potato (Ipomoea batatas) Using Electroporation Method
Aims: The purpose of this study is to get transformants by using the seeds of sweet potato and the instrument of NEPA21, an electroporation method. Study Design: As the first step, we used grafting method to get seeds fr...
Bacterial Synthesis of Silver Nanoparticles by Culture Free Supernatant of Lactic Acid Bacteria Isolated from Fermented Food Samples
Aim: Biosynthesis of silver nanoparticles (SNPs) using culture free supernatant (CFS) of Lactic acid bacteria (LAB). Study Design: To biosynthesize, characterize and to determine the antibacterial potential of silver na...