Assessment of plasma and salivary antioxidant status in patients with recurrent aphthous stomatitis.
Journal Title: RSBO - Year 2011, Vol 8, Issue 3
Abstract
Objective: The purpose of this study was to evaluate the antioxidant levels in plasma and saliva of patients with recurrent aphthous stomatitis (RAS) and healthy controls. Material and methods: Forty patients with RAS and 40 health controls were included into the study. Superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSHPx) activities and uric acid (UA) levels were measured in plasma and saliva. Chi-square and Student’s t-test was used to estimate the significance between parameters. P value less than 0.05 was considered statistically significant. Results: Plasma analysis showed significantly decreased SOD and CAT activities, and UA level in RAS patients compared to control group. Plasma GSHPx activity was significantly higher in RAS patients. In saliva, SOD and CAT activities, and UA levels were significantly higher in RAS patients, while GSHPx activity was lower compared to control. Conclusion: Plasma and saliva antioxidant system is affected in RAS patients and both may be considered as an appropriate indicator of antioxidant status of body.
Authors and Affiliations
Sudhanshu Saxena
Keywords
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