Assessment of Profile of 150 Patients with Spinal Cord Tumour: An Institutional Based Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Background: Primary spinal cord tumors represent 2-4% of all neoplasms of the CNS. Early recognition of the signs and symptoms of primary spinal cord tumors allows for early treatment, potentially minimizes neurologic morbidity and improves outcome. Hence; we planned the present study to assess the profile of patients with spinal cord tumour. Materials & Methods: The present study included assessment of patients presenting with spinal cord tumour. Clinical, histological and imaging data of 150 cases of spinal cord tumour surgically treated at Department of Neurosurgery, N. H. L. Municipal Medical College, Ahmedabad, Gujarat (India) over a period of 2005 to 2015 were collected and analyzed. Patients were classified on basis of age, sex, duration of symptoms and neurological status before surgery. Tumours were categorized according to histology and neuroanatomical location. Follow up at 1 month, and 6 month to see surgical outcome in relation to histological grade, site and pre op neurological deficit. All the results were compiled and analyzed by SPSS software. Results: 75% of schwannomas were IDEM and others were extradural and 3 cases of dumbbell shwannomas with intrathoracic extension. All meningiomas were IDEM, Astrocytomas and ependymomas were intramedullary. Metastasis was found extradurally and was adenocarcinoma, follicular carcinoma of thyroid and renal cell carcinoma on histopathology. All cases of L1 and above level tumor were given 1 gram methylprednisolone intraoperatively at time of induction and in case of intramedullary tumors it was given as per spinal injury regimen. Radiotherapy was given in malignant lesions. Conclusion: The most important predictive factor for the outcome is the duration of symptoms before surgery. This time factor is important because it partly allows predicting the functional results after surgery.
Authors and Affiliations
Tushar Soni, Jasdeep Singh, Bhagirath More, Amisha Sidhu
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