Assessment of Relationship between Chronic Periodontitis and Serum Vitamin D Status among Women during Pregnancy- A Case Control Study
Journal Title: Scholars Journal of Dental Sciences - Year 2018, Vol 5, Issue 3
Abstract
Abstract: Periodontal disease is one of the most common chronic infectious diseases, characterized by the loss of periodontal attachment leading to tooth loss. The prevalence of such disease in pregnancy ranges around 40%. Periodontal disease, as a source of persistent infection, may induce systemic inflammatory responses that increase the risk of adverse pregnancy outcomes. The aim of this study was to assess, compare and to correlate periodontal clinical parameters to the levels of vitamin D in Serum in pregnant women with plaque induced chronic periodontitis. The study included 49 otherwise systemically healthy pregnant women in their second trimester who were under prenatal vitamin D supplement (200 IU/day), with age ranging between 20-30 years. They were divided into four groups based on the severity of clinical attachment loss, Group I with healthy periodontal status, Group II with mild periodontitis, Group III with moderate periodontitis and Group IV with severe periodontitis. Biochemical assay of serum vitamin D was done using spectrometer. The levels of vitamin D in serum were significantly reduced in pregnant women with periodontitis group when compared to healthy controls. A statistical significant difference existed in mean the levels of vitamin D in serum of all groups studied with p-value< 0.001. Pearson correlation matrix test was applied to correlate the levels of vitamin D in serum and periodontal clinical parameters. The present study indicated that negative correlation was observed between all clinical parameters (mean plaque score and percentage of gingival bleeding sites, probing pocket depth and clinical attachment loss) and the levels of vitamin D and Serum vitamin D level deficiency has a negative influence on periodontal health in pregnancy.
Authors and Affiliations
Dr. G. Ramaprabha, Dr. R. Mythili Swaminathan, Dr. S. Senthil kumar, Dr. S. Rajasekar, Dr. John William Felix, Dr. Sethupathy
Keywords
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