ASSESSMENT OF RENAL DYSFUNCTION IN CHRONIC LIVER DISEASES
Journal Title: IJSR-International Journal Of Scientific Research - Year 2018, Vol 7, Issue 3
Abstract
Objectives: Renal impairment in Patients with chronic liver disease is a common phenomenon and is a functional impairment. It seems difficult for the assessment of renal function abnormalities by normal parameters. We aimed to determine the usefulness of creatinine clearance by timed urine collection and Cockcroft Gault formula and Serum creatinine as parameters in assessing renal function in this cohort of patients and also to find if etiology of chronic liver disease has a bearing on renal dysfunction. Material and methods: Renal parameters of 200 patients with chronic liver disease were studied to assess the reliability of the each parameter. Results: In the present study, Only 22% of alcoholics have clearance more than 60ml/min. 58% patients were found to have creatinine clearance more than 60ml/min by Cockcroft Gault formula while only 36% Patients have that by timed urine collection where the difference was found to be statistically significant (P value<0.01). Cockcroft Gault formula overestimates probably due to disparity in weight due to fluid retention. Conclusion: The most reliable Parameter in our clinical setup is Creatinine clearance by timed urine collection. Presence of Ascites, low serum albumin levels and Alcoholic etiology had more predisposition to renal impairment, however, a larger study with more number of patients can throw more light.
Authors and Affiliations
Dr Prahallad Chandra Mishra, Dr Kamal Lochan Behera, Dr Pilla Rakesh, Dr Bh V K Praveen Varma, Dr Aswini Kumar Sahoo
Keywords
Related Articles
- EP ID EP506438
- DOI -
- Views 43
- Downloads 0
Evaluation Of Role Of USG-Guided FNAC In Intra-Abdominal Masses
Background – FNAC of intraabdominal Masses is a routine procedure now a days . Confident diagnosis can be made in combination with other modalities such as USG, CT Scan. It can be substitute to for surgical procedure lik...
INTERACTIVE TEACHING IN ANATOMY LECTURES: PERSPECTIVE OF 1ST PROFESSIONAL MBBS STUDENTS.
Background: Lectures are the most commonly used method for a large group teaching in medical education. In traditional lectures students are passive receivers of information. Introduction of interactive techniques break...
STUDY OF ECTOPIC PREGNANCY AT TERTIARY CARE CENTER
Ectopic Pregnancy is the one in which the blastocyst implants anywhere other than the endometrial lining of the uterine cavity.Ectopic pregnancy has always challenged ingenuity of the obstetrician and Gynecologist by its...
Pulmonary and Extrapulmonary Causes of Acute Respiratory Distress Syndrome (ARDS) with Thrombocytopenia in Adults Admitted in Intensive Care Areas in A Tertiary Care Hospital
Background:Acute Respiratory Distress Syndrome (ARDS) is caused by pulmonary injuries to the lung like community acquired pneumonia (CAP), aspiration, trauma, tuberculosis, etc. and extrapulmonary injuries like sepsis, m...
HEPATITIS C VIRUS AMONG HEALTH CARE WORKERS AND THE RISK FACTORS CONTRIBUTING FOR ITS INFECTION
Back ground: Hepatitis C Virus (HCV) infection is one of the leading causes of morbidity and mortality in under-developed countries like Yemen. According to an estimate, 2.0 % of Yemeni's total population suffers from HC...