Assessment of retrocochlear hearing pathway activity in infants with central nervous system impairment occurring as an effect of perinatal asphyxia
Journal Title: Otolaryngologia Polska - Year 2008, Vol 62, Issue 4
Abstract
Introduction. The most often changes in the central nervous system (CNS) occurring as an effect of perinatal asphyxia are found to be hypoxic-ischemic encephalopathy (HIE) in term newborns, peri- (PVH) or intraventricular hemorrhages (IVH) and periventricular leukomalacia (PVL) in preterm neonates. Chronic hypoxia is considered to affect the brainstem in infants, especially nuclei of the hearing pathway are vulnerable to low oxygen level. The aim of the study was to carry out the objective assessment of the retrocochlear hearing pathway activity using ABR in infants with CNS impairment occurring as an effect of perinatal asphyxia, imaged during trans-fontanel ultrasonography. Material and methods. To the investigation 36 infants with HIE, IVH or PVL were included, the control group encompassed 32 born at term, health children. ABR recordings were performed in 3 months old children using Nicolet Spirit System for clicks of 85 and 80 dB nHL. Results. No differences were found between latencies of waves I and II. ABR latencies of waves III, IV, V and interpeak latencies I–III, III–V, I–V were signifi cantly delayed in InvG when compared to control patients. In conclusion, the brainstem activity in infants with CNS involvement as an effect of perinatal asphyxia is lower comparing to health children. Subclinical abnormalities as prolonged synaptic transmission of electric signal in retrocochlear auditory pathway were revealed.
Authors and Affiliations
Agnieszka Widziszowska, Grzegorz Namysłowski, Anna Genge, Agata Hajduk, Urszula Godula-Stuglik
Keywords
Related Articles
- EP ID EP51561
- DOI -
- Views 116
- Downloads 0
Reconstruction of the hypopharynx and cervical esophagus with gastric pull-up technique in the patient with recurrence carcinoma of the hypopharynx
Patient with hypopharyngeal cancer are difficult to treat because they usually present with advanced disease, poor general health status and severe nutritional problems. Because of the poor prognosis, careful considerati...
The role of functional nasal surgery in the treatment of obstructive sleep apnea syndrome
Introduction: Nasal obstruction is widely mentioned among the factors influencing pathophysiology of obstructed breathing disorders during sleep. However numerous observations confirms such relation, influence of nasal s...
Zastosowanie izotonicznego roztworu NaCl u chorych z ostrym zapaleniem błony śluzowej nosa i zatok przynosowych
Wstęp<br/><br/>
Wpływ wybranych czynników kliniczno-morfologicznych na wyniki leczenia chorych z zawansowanym rakiem krtani
Introduction: The aim of the study was to indicate independent prognostic factors of treatment in group of patients with advanced cancer of the larynx. Material and method: The paper presents results of univariate and mu...
The usefulness of evaluation of: ferritin, ultrasensitive CRP and tissue specific polypeptide 18th (TPS) in assessment of therapy efficacy in patients with nasal polyps
Background: Chronic rhinosinusitis with nasal polyps is social, clinical and cost-effective problem, by reason of bothersome symptoms, chronic nature of the disease, tendency to recur and lack of satisfying treatment. Ai...