Assessment of retrocochlear hearing pathway activity in infants with central nervous system impairment occurring as an effect of perinatal asphyxia

Journal Title: Otolaryngologia Polska - Year 2008, Vol 62, Issue 4

Abstract

Introduction. The most often changes in the central nervous system (CNS) occurring as an effect of perinatal asphyxia are found to be hypoxic-ischemic encephalopathy (HIE) in term newborns, peri- (PVH) or intraventricular hemorrhages (IVH) and periventricular leukomalacia (PVL) in preterm neonates. Chronic hypoxia is considered to affect the brainstem in infants, especially nuclei of the hearing pathway are vulnerable to low oxygen level. The aim of the study was to carry out the objective assessment of the retrocochlear hearing pathway activity using ABR in infants with CNS impairment occurring as an effect of perinatal asphyxia, imaged during trans-fontanel ultrasonography. Material and methods. To the investigation 36 infants with HIE, IVH or PVL were included, the control group encompassed 32 born at term, health children. ABR recordings were performed in 3 months old children using Nicolet Spirit System for clicks of 85 and 80 dB nHL. Results. No differences were found between latencies of waves I and II. ABR latencies of waves III, IV, V and interpeak latencies I–III, III–V, I–V were signifi cantly delayed in InvG when compared to control patients. In conclusion, the brainstem activity in infants with CNS involvement as an effect of perinatal asphyxia is lower comparing to health children. Subclinical abnormalities as prolonged synaptic transmission of electric signal in retrocochlear auditory pathway were revealed.

Authors and Affiliations

Agnieszka Widziszowska, Grzegorz Namysłowski, Anna Genge, Agata Hajduk, Urszula Godula-Stuglik

Keywords

Related Articles

Microtia: isolated defect of hearing organ, or syndrome forming collection of abnormalities

Congenital malformations of the external ear are relatively rare, however gradual increase in their frequency has been observed in the last years. These defects can occur as isolated congenital malformations, but they ca...

Operative and Postoperative Management of Patients after Neck Surgery

SUMMARY Introduction: Cancer patients after neck surgeries require specific operative and postoperative management, which to some extent determines the finał outcome of the surgery. Such procedures require particular att...

Guzy tylnego dołu czaszki jako przyczyna nagłego pogorszenia słuchu i/lub wystąpienia zawrotów głowy

SUMMARY Introduction: The aim of the work was to analyse sudden deterioration of hearing and/or vertigo occurrence as an early symptom of posterior cranial fossa tumours. Material and methods: Among 1.394 people who repo...

Rak zatoki szczękowej u 24-letniego mężczyzny, aspekty opieki holistycznej

SUMMARY The aim of this study is to report a carcinoma affecting the maxillary sinus of a 24-years old man. Malignant tumors of the nasal cavity and paranasal sinuses are rare and a very heterogeneous group of tumors. Th...

Contemporary noise-induced hearing loss (NIHL) prevention

Hearing impairment caused by noise, traditionally called – depending on the duration of exposure - acute or chronic acoustic trauma, includes, in addition to presbyacusis, the most common adult population of hearing impa...

Download PDF file
  • EP ID EP51561
  • DOI -
  • Views 117
  • Downloads 0

How To Cite

Agnieszka Widziszowska, Grzegorz Namysłowski, Anna Genge, Agata Hajduk, Urszula Godula-Stuglik (2008). Assessment of retrocochlear hearing pathway activity in infants with central nervous system impairment occurring as an effect of perinatal asphyxia. Otolaryngologia Polska, 62(4), 471-475. https://europub.co.uk/articles/-A-51561