Assessment of Serum Levels of Malondialdehyde, Antioxidant Vitamins (A, E, C), and Lipid profile in Sudanese With type 2 Diabetes Mellitus
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 6
Abstract
A cross sectional study conducted during the period from May 2013 to December 2015 to assessment the serum levels of malondialdehyde (as a marker of lipid per oxidation), antioxidant vitamins (A, E, C), and zinc in addition to lipid profile in Sudanese with type 2 diabetes mellitus compared to healthy volunteers. Three hundred of diabetic patients who attended ADC centre for routine follow up and a control group of 100 healthy subjects (non-diabetic). Blood specimens were collected from both groups, and plasma levels of Malondialdehyde, antioxidant vitamins (A, E, C), in addition to fasting plasma glucose and glycetaed hemoglobin (HbA1c) were determined. Age and gender of the test group were matched with the control group. The results of the study indicate a significant raised in the means of the plasma levels of malondialdehyde, fasting plasma glucose, cholesterol, LDL, triglyceride, and HbA1c of the test group when compared with healthy control group subjects, whereas the means of the plasma levels of antioxidant vitamins (A, E, C),HDL and zinc showed significant reduction when compared with that of control group In conclusion, the present study indicate that the plasma levels of MDA, antioxidant vitamins (A, E, C) and ,FPG, lipid profile and HbA1c are important markers for evaluation of oxidative stress, antioxidant status, and glycemic control of diabetic patients respectively. Keywords: Diabetes mellitus, Oxidative stress, Malondialdehyde, vitamin C, E, A.
Authors and Affiliations
Abd Elgadir A. Altoum, Isam M. Sadig
Keywords
Related Articles
- EP ID EP373840
- DOI -
- Views 51
- Downloads 0
Study the Effect of Pranayama on Academic Performance of School Students of IX and XI Standard
Fifty students of IX and XI std, whose ages ranged from 13 to 18 years, where assessed by GC Ahuja group test of Intelligence (GGTI), at the beginning and again at the end of 6 months period during which the students wer...
Comparative Study of Epidural Ropivacaine versus Ropivacaine Clonidine
Abstract: This is a prospective randomised study conducted at yashoda hospital with the aims to determine the qualitative and quantitative aspects of epidural block, hemodynamic effects, and postoperative pain relief of...
A comparative study of diabetic and non-diabetic foot infections with reference to etiopathogenesis, clinical features, and outcome
The present study was conducted in Mamata medical college, Khammam, Telangana state. The principle aim of the study was to compare foot infections among diabetic and non-diabetic patients. It is comprised of 100 cases ad...
Management of Amelogenesis Imperfecta: Report of Three Cases
Amelogenesis Imperfecta (AI) is a genetic disease affecting primary and permanent tooth enamel. The incidence varies between 1:700 to 1:4000. The clinical findings include enamel defects, tooth sensitivity, poor dental a...
Left Ventricle Non Compaction-Like Cardiomyopathy in a Patient with Systemic Lupus Erythematosus
Abstract: Left ventricular noncompaction (LVNC) is a rare genetic cariomyopathy. It is thought to be due to the failure of condensation of the myocardial meshwork of fibers during intrauterine life, leading to persistenc...