Assessment of Some Cardiac Markers in Apparently Healthy Active Tobacco Male Smokers in Nnewi, South Eastern, Nigeria.
Journal Title: IOSR Journal of Nursing and health Science - Year 2019, Vol 7, Issue 1
Abstract
Background: Smoking is regarded as a social activity but with adverse effects. This study investigated the cardiac status of active tobacco smokers in Nnewi, South Eastern, Nigeria. Methods: A total of 100 subjects compromising of 50 apparently healthy active and non- smokers respectively were recruited for the study. Their blood pressure readings and weight were obtained. Well – structured questionnaire was used to obtain their bio-data. Blood sample was collected from each subject and estimated for apolipoproteins (Apo A-1, Apo B), creatine kinase –MB (CK-MB) and Troponin I. Standard routine analyses were used for estimation of parameters. Data obtained were statistically analyzed using student t-test and Pearson r correlation. Results: The results showed that the mean serum levels of ApoA-1, ApoB, CK-MB and Troponin I were significantly higher in active tobacco smokers than in the control groups at p< 0.05 respectively. Also the mean serum activity of CK-MB was significantly higher in active tobacco smokers than in the control groups at p< 0.05. Similarly, the mean levels of systolic and blood pressure (SBP, DBP) and weight (WT) were significantly higher in active tobacco smokers than in the control groups at p< 0.05 respectively. There was positive correlation between age vs ApoA-1, CK-MB vs WT, WT vs ApoA-1, WT vs ApoB and WT vs CK-MB in control groups than in active tobacco smokers at p <0.05 respectively. Similarly, there was negetive correlation between ApoA vs SBP, Troponin I vs age, CK-MB vs ApoA-1, SBP vs WT, SBP vs SBP, DBP vs ApoA-1, DBP vs DBP, WT vs age in control groups than in active tobacco smokers at p <0.05 respectively. There was positive correlation between age vs ApoA-1, Troponin I vs SBP and negative correlation between Apo B vs SBP, CK-MB vs DBP in active tobacco smokers respectively. Conclusion: The study observed elevated levels in ApoA-1, ApoB, Troponin I, CK-MB, SBP, DBP and weight in the active smokers. There were increasing and attenuating associations of parameters observed in the group studied. These findings may suggest that the incidence of coronary heart disease may be associated with smoking. Hence, smoking is needed to be refrained from as part of modifiable risk factors in the control of heart diseases.
Authors and Affiliations
I. P. Ezeugwunne, E. C. Ogbodo, R. A. Analike, O. A. Onyegbule, V. N. Oguaka, A. K. Amah, O. Nnabude, S. C. Meludu
Keywords
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- EP ID EP435164
- DOI 10.9790/1959-0701035054.
- Views 108
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