Assessment of Vitamin D Levels in Women with Polycystic Ovarian Syndrome
Journal Title: The Egyptian Journal of Hospital Medicine - Year 2018, Vol 70, Issue 4
Abstract
<strong>Background: </strong>polycystic ovary syndrome (PCOS) is the most common endocrine disorder in women of reproductive age, with a prevalence of 6–10% in the general population. PCOS is characterized by the following: ovulatory dysfunction resulting in oligo-amenorrhea and/or anovulation, hyperandrogenism and/or hirsutism and the presence of polycystic ovarian morphology by ultrasound. Vitamin D also plays a physiologic role in reproduction including ovarian follicular development and luteinization via altering anti-Müllerian hormone (AMH), signaling, follicle-stimulating hormone sensitivity and progesterone production in human granulosa cells.<strong> Aim of the Work: </strong>this study aimed to compare levels of vitamin D in women with PCOS and healthy fertile women.<strong> Patient and Methods:</strong> this case control study was conducted in Ain Shams Maternity hospital in outpatient infertility clinics and family planning clinic during the period from March 2017 to October 2017. It was included 40 women diagnosed with PCOS based on Rotterdam criteria and 40 fertile women without PCOS who were recruited from family planning clinic. <strong>Results: </strong>25(OH) vitamin-D level was significantly lower in PCOS group than in the control group. <strong>Conclusion: </strong>25(OH) vitamin-D was significantly lower in PCOS group than in the control group, but not sufficient to be a diagnostic tool for PCOS. <strong>Recommendation:</strong> larger studies are still needed to clarify the rule of vitamin D in infertility.
Authors and Affiliations
Eman Helal
Keywords
Related Articles
- EP ID EP583532
- DOI 10.12816/0043811
- Views 131
- Downloads 0
Role of Magnetic Resonance Imaging in evaluation of postoperative knee surgery
<strong>Background: </strong>MRI has high sensitivity and specificity regarding the assessment of the post-operative knee joint. <strong>Purpose: </strong>to assess the role of MRI in evaluation of the post-operative kne...
Role of Rebamipide and \ or Pantoprazole in Preventing Dexamethasone Induced Gastritis in Senile Male Albino Rats
Aim of the work: gastritis is the inflammation of the lining of the stomach .It is caused by many factors like infection by Helicobacter pylori, drug induced such as aspirin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs...
Emergency Management of Upper GI Variceal Bleeding
<strong>Background:</strong> Upper gastrointestinal bleeding is the most common gastrointestinal cause of admission in emergency departments worldwide with about 10% inpatient mortality rate that has not decreased during...
The Role of Fibroscan as a Non-Invasive Predictor for Oesophageal Varices in Post HCV Cirrhotic Egyptian Patients With or Without Bilhariziasis
<strong>Background: </strong>Development of oesophageal varices is a major complication that may occur in up to 90% of cirrhotic patients. The endoscopic screening is an invasive procedure. This is why the selection of p...
Interferon Lambda 4 Gene (IFNL4) Linked to Hepatitis C virus clearance, treatment
Background: AdesignatedIFNL4 gene, encoding the interferon-λ4 protein (IFNL4), which is moderately similar to IFNL3, is more strongly associated with HCV clearance in individuals of African ancestry, whereas it provides...