Assessment of vitamin D supplementation in the Warsaw’s children after infancy – a preliminary study
Journal Title: Postępy Nauk Medycznych - Year 2014, Vol 27, Issue 10
Abstract
Introduction. An adequate concentration of blood 25-hydroxyvitamin D promotes pleiotropic actions of vitamin D.Aim. The aim of the study was to assess the vitamin D status in the Warsaw’s children after infancy. Study data were collected from records of children hospitalized in the Department of Pediatrics and Endocrinology in the period August-December 2012.Material and methods. Study group included 257 children: 132 girls and 125 boys, mean age 10.44 ± 4.25 years. Serum 25-hydroxyvitamin D – 25(OH)D – concentrations were measured at hospitalization with Microparticles Chemiluminescence (Abbott, Wiesbaden, Germany). The study analysis included the correlations between 25(OH)D concentration and selected variables.Results. Mean 25(OH)D concentration was estimated at 23.86 ± 7.96 ng/ml. Only 21.40% of children approximated values higher than 30 ng/ml. Prior vitamin D supplementation was provided to 38.13% of children. 159 children had no supplementation whatsoever, 64 children were supplemented at a dose of 500 IU and 34 children at a dose of 1000 IU. 25(OH)D concentration in children supplemented with vitamin D was significantly higher than in patients without supplementation (p < 0.005). A statistically significant difference was observed between mean 25(OH)D level in pubertal and pre-pubertal children (p = 0.002). The mean 25(OH)D concentration was significantly lower in obese children than in other patients (p = 0.00001).Conclusions. According to our study data vitamin D dose of 500-1000 IU/d is required to maintain the current level in the blood. Few children receive vitamin D supplementation which favors the maintenance of adequate 25(OH)D concentration. During puberty as well as in obese children the requirement for vitamin D is higher.
Authors and Affiliations
Ada Borowiec, Monika Milczarek, Katarzyna Wyborska, Agata Cichal, Anna Kucharska
Keywords
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