Assessment ofCalcium Carbide andNatural Ripened Pawpaw (Carica Papaya) Fruits onBiochemical Parameters of WistarRats
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2022, Vol 2, Issue 07
Abstract
This research was aimed at assessing calcium carbideand naturalripened pawpaw (Carica papaya) fruit on the biochemical parameters of the Wistar rats. Twenty four (24) adult Wistar rats weighing between 126.9-213.3g was used for this study. The experimental Wistar rats were grouped into three and were allowed to acclimatize for two weeks at libitum. Five (5) ml/kg of natural and calcium carbide ripenedpawpawfruit juice were administered orally.At the end of the four weeksfeeding period, the rats were sacrificedthrough cervical dislocation. Blood was collected by cardiac puncture, using 5ml syringes and 23G needles into blood sample containers for biochemical analysis using thestandard biochemical methods.The renal, hepatic, cardiac, heartand lipid profile parametersanalyzed were albumin, total protein, urea, creatinine, Alkaline Phosphatase (ALP), Alanine aminotransferase (ALT),total bilirubin, Aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and total cholesterol and were compared with the naturally ripened pawpaw fruit group. Allmean values of total protein, total cholesterol, lactate dehydrogenase and creatinine levels of calcium carbide ripened pawpaw fruit juice fed groupwere significantly higher when compared with the natural ripened pawpaw fruit juice. Meanwhile, albumin, total bilirubin, urea,ALT, AST and ALP levels of calcium carbide ripened fruit juice fed group were lower when compared with the natural ripened pawpaw fruit juice. Statistically, there were no significant differences of albumin and total protein parameters at 95% confidence level (P < 0.05). In conclusion, the elevated levels of creatinine, total cholesterol and lactate dehydrogenase may result to kidney injury, cardiovascular and heart diseases. There is therefore need for institutional and legislative strengthening as well as enforcement to prevent the use of calcium carbide in the ripening of pawpawand other fruits
Authors and Affiliations
Ogoun Timipa Richard
Keywords
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- EP ID EP731734
- DOI 10.47191/ijmscrs/v2-i7-11
- Views 44
- Downloads 0
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