Association between bh4/bh2 ratio and Albuminuria in Hypertensive Type -2 Diabetic patients
Journal Title: Journal of Clinical Nephrology - Year 2017, Vol 1, Issue 1
Abstract
Endothelial dysfunction and inflammation play a key role in the pathophysiology of diabetic nephropathy; Tetrahydrobiopterin (BH4) is an essential cofactor for nitric oxide synthase, when BH4 is reduced to dihydrobiopterin (BH2), endothelial dysfunction is induced.
Authors and Affiliations
JA Herrera, KC Arana-Pazos, LD Valle-Mondragon, CG García, AF Rubio-Guerra
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Association between bh4/bh2 ratio and Albuminuria in Hypertensive Type -2 Diabetic patients
Endothelial dysfunction and inflammation play a key role in the pathophysiology of diabetic nephropathy; Tetrahydrobiopterin (BH4) is an essential cofactor for nitric oxide synthase, when BH4 is reduced to dihydrobiopter...