Association Between Helicobacter pylori and Pharyngolaryngeal Carcinomas: Role in Development and Prognostic Significance
Journal Title: Mediterranean Journal of Infection, Microbes and Antimicrobials - Year 2019, Vol 8, Issue 1
Abstract
Helicobacter pylori is a worldwide common bacteria that infects humans. This Gram-negative microorganism is microaerophilic, spiral or curved shaped, and urease, catalase and oxidase-positive. It has the ability to live in the acidic environment of the gastric mucosa. It has been shown that H. pylori plays a role in the development of gastric ulcers and malignant lesions. Furthermore, it was reported that H. pylori may be a cause of several systemic illnesses such as cardiovascular, dermatologic, immunologic, neurologic, hematologic, ophthalmologic, gynecologic, endocrine, and hepatobiliary diseases. In addition, positive or negative correlations between H. pylori infection and rhinitis, sinusitis, adenoiditis or adenoid hyperplasia, otitis media, tonsillitis, or tonsil hypertrophy have been demonstrated in various studies in the literature. However, H. pylori’s role in the pathogenesis or association with these diseases remains controversial. Some studies reported that systemic immune and inflammatory responses against H. pylori might cause some systemic diseases as well as different types of malignancies. Although there are studies about the role of H. pylori in benign and malignant diseases of the upper and lower respiratory tract, further studies are needed to reveal the pathophysiological relationship between H. pylori infection and respiratory diseases. The aim of this review was to summarize the studies that reported either a positive or negative relationship between H. pylori and benign and malignant diseases of the respiratory tract.
Authors and Affiliations
Tuba BAYINDIR, Yaşar BAYINDIR, Çiğdem FIRAT KOCA, İsmail DEMİR, Barış OTLU
Keywords
Related Articles
- EP ID EP689263
- DOI 10.4274/mjima.galenos.2019.2019.2
- Views 169
- Downloads 0
Evaluation of the Side Effects of Antiretroviral Treatment
Introduction: The frequency of antiretroviral therapy (ART)-induced side effects varies in HIV-infected patients. In this study, we aimed to compare drug-induced side effects developing in patients receiving different AR...
Investigation of the Prevalence of Group A Beta-haemolytic Streptococcus and Efficiency of Streptococcus Rapid Antigen Test in Patients Prediagnosed with Acute Tonsillopharyngitis in a University Hospital
Introduction: Acute tonsillopharyngitis is the most important infectious cause of hospital admission in pediatric age groups. The aim of this study was to investigate the prevalence of group A beta-hemolytic streptococci...
Lyme Disease
Lyme disease (LD), also known as Lyme borreliosis and carried by Ixodes ticks, is the most common zoonotic disease in the northern hemisphere. Although the prevalence of the disease in Turkey is not known exactly, seroep...
Is Nurse Workforce Sufficient in Intensive Care Units in Turkey? Results of the Multicenter Karia Study
Introduction: In this multicenter study, we analysed the magnitude of healthcare worker (HCW) [infection control practitioner (ICP), nurses and others] workforce in hospitals participated in the study. Materials and Met...
Idiopathic CD4 Lymphocytopenia (HIV-Negative AIDS): Case Report and Literature Review
Idiopathic CD4 lymphocytopenia (ICL), also known as non-HIV AIDS, is a rare disease characterized by opportunistic infections, malignancies, and autoimmune diseases. Idiopathic CD4 lymphocytopenia is defined as CD4+ T-ly...