Association between infection with Chlamydia pneumonia and cerebral noncardioembolic ischemic stroke
Journal Title: Neurology Letters - Year 2022, Vol 1, Issue 1
Abstract
Introduction: Stroke is the third most common cause of mortality and the most common disability disorder among adults. We aimed to study the relationship between Chlamydia pneumonia infection and non-cardio Ambulatory ischemic stroke. Methods: This case-control study was performed on 162 patients with non-cardio ambulatory ischemic stroke admitted to Shahid Beheshti Hospital of Kashan in 2019 as the case group and patients with neurological headache and degenerative diseases as the control group. After filling out the questionnaire for all subjects, we took blood samples. We analyzed all three anti-chlamydia pneumonia antibodies (IgM, IgG, IgA) by ELISA method after data were analyzed by Chi-square and Fisher tests. Results: The findings of this study showed that positive IgA in the stroke group was significantly higher than in the control group (p=0.001); it was also found that the risk factors of HTN (p=0.001), HLP (p=0.001), DM (p=0.001), and age (p = 0.049) were significantly higher in the stroke patients’ group than the control group. On the other hand, there was not a significant difference in serum IgG level (p = 0.349), IgM (p = 0.745), smoking (p = 0.211) and gender (p = 0.157) in understudied groups. Conclusion: Chlamydia IgA antibodies can be a complementary tool for predicting prognosis and monitoring new therapies for ischemic stroke. This study provides a way for further studies, especially with other markers of acute and chronic systemic Chlamydia pneumonia infection. Antibiotic treatment significantly helps to reduce mortality and stroke complications.
Authors and Affiliations
Seyed Amir Abbas Ahadiat,Seyed-Ali Masoud,Mohammad sadegh Khorshidi,Zeinab Hosseinian,Mahbobeh Haghshenas Jazi,Ebrahim Kouchaki,Javad Abolhasani,
Keywords
Related Articles
- EP ID EP709696
- DOI 10.52547/NL.1.1.39
- Views 53
- Downloads 0
Role of Biomaterials in treatment of Alzheimer’s disease: A literature review
Currently, five medications have been approved by the FDA to treat Alzheimer's disease (AD); Donepezil, which is used at all stages of AD, galantamine, and rivastigmine for mild to moderate stages, and Memantine and a co...
What should we do to reduce the complications of Deep brain stimulation in Parkinson's disease?
Parkinson's Disease (PD) is one of the most common neurodegenerative disorders. Recently, Deep Brain Stimulation (DBS) was proposed as a potential therapeutic approach for PD patients. This procedure has side effects tha...
Acute relapse of Multiple Sclerosis (MS) in an adolescent patient after Tuberculin skin test (TST): a case report
Activation of MS as a result of bacterial and viral infections is proposed by various studies. However, immune responses initiated by a bacterial antigen can rarely lead to the activation or occurrence of MS. Hereby, we...
Central nervous system autoimmune diseases associated with COVID-19: Comprehensive review
The first appearance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) named coronavirus disease 2019 (COVID-19) was reported from Wuhan in December 2019. While this virus displays several respiratory manif...
Transient global amnesia associated with acute bacterial endocarditis; A case report
Introduction: Transient global amnesia (TGA) is a sudden loss of memory without definite etiology. Some cardiac conditions like myocardial infarction, mitral valve prolapse, takotsubo syndrome, and arrhythmias have been...