Association between Obesity and Coronary Heart Disease Risk among Saudi Subjects at Madinah Region

Journal Title: Journal of Pharmaceutical Research International - Year 2016, Vol 12, Issue 3

Abstract

Purpose: To characterize the association between major cardiovascular diseases risk among Saudis and their body mass index (BMI). Methods: A cross-sectional study was conducted (April to June 2015) to investigate the expected 10 years risk for cardiovascular diseases (CVD) among Saudi subjects (age range 20-70 years) using Framingham Risk Score (FRS) with respect to their BMI (analyzed October 2015). Results: In the present study there was a significant association between the 10 years risk of developing CVD and BMI. The results revealed an increase in BMI contributing to significant increase in the 10 years risk of CVD among males. The overall distribution of FRS among males regardless the BMI category as a percentage of the total male subjects revealed that males were at low, medium and high CVD risk of 71.4%, 14.27% and 14.3%, respectively. However, female subjects showed 91.5%, 4.8% and 3.6% at low, medium and high FRS, respectively. In addition, significant increases in the Odd ratio amounting to 4.58 and 5.24 among intermediate and high risk males in comparison with female ones, respectively. Conclusions: BMI strongly associated with the expected 10 years FRS for CVD. Moreover, there was gender specific susceptablity for CVD risk among Saudi males compared to female ones. Socioeconomic, behavioral, awareness about healthy choices and genetic characteristics of obesity should be taken in consideration since extrapolating other population's studies to Saudi one might be misleading.

Authors and Affiliations

Sherif Y. Saad, Mohamed M. M. Abdel-Latif

Keywords

Related Articles

Effect of Different Doses of Sitagliptin in Treatment of Experimentally Induced Colitis in Mice

Ulcerative colitis is a chronic, relapsing and progressive inflammatory bowel disease (IBD) characterized by diffused mucosal inflammation of the colon. DPP-IV inhibitors may provide a new treatment strategy for IBD. Thu...

Comparative Study of the Physical Characteristics of Some Commercially Available Brands of Amoxicillin Capsules

Aim: To assess the quality of 10 brands of Amoxicillin Trihydrate 500 mg capsules. Study Design: Experimental. Place and Duration of Study: Experimental drugs were purchased from pharmacy in Okada and Benin and experime...

In vitro Antioxidant, Antihyperglycaemic and Antihyperlipidaemic Activities of Ethanol Extract of Lawsonia inermis Leaves

Aim: This present study investigated the free radical scavenging activities, antihperglycaemic and antihyperlipidaemic activities of ethanol extract of Lawsonia inermis leaves. Study Design: Twenty male rats were randoml...

In silico Identification of Novel Potential BACE-1 Inhibitors for Alzheimer’s Disease Treatment: Molecular Docking, Pharmacophore Modeling and Activity and Synthetic Accessibility Predictions

Aims: Alzheimer's Disease (AD) is a progressive neurodegenerative disease accompanied by loss of memory and cognition. With its causes still unknown, one of the main hypotheses related to its pathogenesis is the amyloida...

Effect of Formulation Variables on the Release of Letrozole from Natural Biodegradable Polymeric Implants

Aim: Letrozole, a non-steroidal aromatase inhibitor, prevents the body from producing its own estrogen. The objective of the present study was to explore the fabrication and evaluation of natural biodegradable polymeric...

Download PDF file
  • EP ID EP342146
  • DOI 10.9734/BJPR/2016/26382
  • Views 110
  • Downloads 0

How To Cite

Sherif Y. Saad, Mohamed M. M. Abdel-Latif (2016). Association between Obesity and Coronary Heart Disease Risk among Saudi Subjects at Madinah Region. Journal of Pharmaceutical Research International, 12(3), 1-8. https://europub.co.uk/articles/-A-342146