Association between Plasma Osmolarity and Mortality in Patients Admitted in ICU at IMCHRC, Indore
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 3
Abstract
Abstract: This research aims to explore the association between serum osmolarity and mortality in patients who are admitted in ICU with a specific category of Hyper Glycemia, Uremia & ACS in ICU of Index Medical College, Indore Total patient studied of 200. Both Genders age between 35-65 years. Patients were divided into three groups disease sub groups based on the diagnosis at admission: cardiac, hyperglycemic& uremia, the association between osmolarity & mortality was evaluated. Strengths and limitations of this study the small sample size. Subgroup analysis based on different admission diagnoses was performed to evaluate the osmolarity of mixed intensive care unit. Osmolarity was calculated in the current study which leads to certain bias despite an optimal equation were used. Using the formula 2x sodium + RBS/ 18+ Urea/2.8. Analysis of the 200 patients revealed relationship between osmolarity and mortality & ICU stay in patients with Hyperglycemic, Hyper Urecemia & Coronary Artery Disease. Both Hypo-osmolarity and hyper natraemia, leading to clinically adverse consequences such as increased in risk of mortality & increase no. of days in ICU cardiovascular, hyperglycemic and renal disorders 34 mortality were noted. 56 hypo osmolarity were associated with increased stay up to 72 hours in ICU. The values of serum osmolarity mortality & mortality were more in patients in Hypo & hyper Osmolarity, with the increasing in no. of days in ICU. Acute coronary syndrome 7–9 Despite the consistency of results hypo-osmolarity but hyper osmolarity was significantly showing is associated with associated with mortality except for extreme increased mortality, hyper osmolarity (=340mmoL/L). In all sub groups, vasopress if use was consistently associated with increased mortality. Hypo-osmolarity is associated with increased mortality in patients who are critically ill but Hper osmolarity as compare to Hypo-osmolarity.
Authors and Affiliations
Dr. Bushra Khanam, Dr. Sudhir Mourya, Dr. Veerendra Singh Patel, Dr. Abhay Sharma
Keywords
Related Articles
- EP ID EP475848
- DOI -
- Views 62
- Downloads 0
Evaluation of CBNAAT over Smear Microscopy for Diagnosis of Tuberculosis in Pediatric Patients
Abstract: Globally, India is a home for more than 25% of global Tuberculosis (TB) burden. Tuberculosis (TB) in children is neglected as diagnosis is challenging due to insufficient specimen material, the scarcity of baci...
Comparative study of Treatment of Premacular subhyaloid Haemmorrhage between conservative Vs Nd-YAG Laser Hyaloidectomy in tertiary care Centre
Premacular subhyaloid hemorrhage is one of the etiologies of sudden visual loss. It might be due to vascular or blood abnormalities or Valsalva retinopathy. Spontaneous absorption of blood may take months and result in m...
An Uncommon Cause of Recurrent Sub-Ileus and Abdominal Pain: Meckel’s Diverticulum Inverted by a Lipoma
Complications of Meckel’s diverticulum are seen rarely in adults. Most common complications are intestinal obstruction and diverticulitis. Obstruction caused by inversion of Meckel’s diverticulum by intestinal tract lipo...
Evaluation of Echocardiographic Systolic Parameters in Pre Eclamptics and Normotensives
Abstract: Early detection of changes in cardiovascular echocardiographic systolic parameters and their comparison with normotensives women. This method was a hospital based prospective case control study carried out in d...
Ochronosis- The Role of Total Hip Replacement: A Case Report and Review of Literature
Alkaptonuria is a rare autosomal recessive, single-gene metabolic disease caused by the lack of the enzyme homogentisic acid oxidase and characterized by black pigmentation of cartilage and other connective tissues. 38 y...