Association between sub clinical hypothyroidism and nonalcoholic fatty liver disease in children
Journal Title: Journal of the Indian Medical Association - Year 2019, Vol 117, Issue 7
Abstract
Non-Alcoholic Fatty Liver Disease is defined as accumulation of fat in Liver cells in absence of excess alcohol consumption. To study the association between sub Clinical Hypothyroidism and NonAlcoholic Fatty Liver Disease in Children. In this cross-sectional study which was done at Department of thyroid and endocrine research in the Institute of Nuclear Medicine & Allied Sciences, Delhi, 30 children in the age group of 10-18 years with Sub Clinical Hypothyroidism were compared with 30 age and sex matched controls. This entire cohort of cases and controls were subjected to anthropometric, biochemical and radiological examination. Bio chemical evaluation included estimation of Free T3, Free T4, TSH, lipid profile and Liver Function Tests. Radiological evaluation included USG of thyroid for echogenicity and presence of nodule. USG of abdomen was done to look for presence of fatty liver. In 53.3% children with sub clinical hypothyroidism had fatty liver on USG compared to 13.3% controls. The prevalence of Non-Alcoholic Fatty Liver Disease in our children was considered higher as compared to general population. Children with sub clinical hypothyroidism are at increased risk of developing NonAlcoholic Fatty Liver Disease.
Authors and Affiliations
Rashmi Aggarwal, Manju Popli
Keywords
Related Articles
- EP ID EP626798
- DOI -
- Views 152
- Downloads 0
Rapid Test (Immunochromatography) Versus Real Time RTPCR in diagnosis of Influenza-A
This is a Prospective study comparing the Efficacy of Rapid Test (Immunochromatography/OSOM Influenza-A & B) Versus Real Time RTPCR in diagnosis of Influenza-A. In 50 Influenza suspects were identified using CDC definiti...
Diaphyseal aclasis : study of imaging pattern and associated deformities
Hereditary multiple exostosis, also known as Diaphyseal aclasis is characterised by development of multiple exostosis. We report two cases of diaphyseal aclasis who presented to the outpatient orthopaedics department of...
Effect of 2-5 years of tobacco chewing on pulmonary function tests
The present work is undertaken to study the effect of 2-5 years of tobacco chewing on pulmonary functions. The study group consisted of 30 male, young, healthy subjects, free from cardiopulmonary diseases and with histor...
Affordable ART for the Masses
Assisted Reproductive Technology (ART) has revolutionized the management of couples with the problem of infertility. It has been available over the last four decades and more than 5 million babies have been born with thi...
Common errors with insulin use and potential solutions
Medication error is the most unacceptable event in the course of treatment. Errors related to the use of insulins are common in clinical practice at various levels. Such errors may lead to serious consequences like episo...