Association between Vitamin-D Status and Cardiovascular Risk among Postmenopausal Women in Kerala Population
Journal Title: Indian Journal of Obstetrics and Gynecology - Year 2018, Vol 6, Issue 3
Abstract
Introduction: cardiovascular diseases (CVD) are the leading cause of morbidity and mortality across the world. Postmenopausal women may have an increased risk of CVD. Vitamin-D (Vit-D) is believed to have an important role in the progression of CVD. Hence the study was undertaken to assess the link between Vit-D and CVD among postmenopausal Kerala population. Materials and Methods: A cross-sectional study was undertaken in 149 postmenopausal women. Demographic parameters were collected by using a questionnaire. Blood samples were collected and Vit-D status of all volunteers was estimated. The sample population was further grouped into three based on the Vit-D status as Vit-D deficient, insufficient and normal groups. Other parameters such as blood glucose, blood pressure, TC, TG, HDL, and LDL were measured and recorded. The result was analyzed by using appropriate statistics. Result: There was a significant difference in the biomarkers of CVD between the test groups. The one way ANOVA between the groups showed a significant difference (p £ 0.05) in body weight, FBS, HDL, and TG. The Person correlation test indicated a negative correlation between Vit-D with SBP, LDL, Apo-B, hsCRP and Lp-PLA2. Whereas a positive correlation was noted with Apo-A1 levels. Conclusion: The result of the present study revealed that there is a significant association between Vit-D status and risk for CVD in the postmenopausal women of Kerala population. The study could reveal the elevated levels of conventional and specific biomarkers for cardiovascular risk.
Authors and Affiliations
P. Mumtaz .
Keywords
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- EP ID EP549582
- DOI 10.21088/ijog.2321.1636.6318.8
- Views 94
- Downloads 0
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