Association of ABO and Rhesus Blood Group with Type-2 Diabetes Mellitus in Northern India: A Cross-Sectional Study
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 3
Abstract
The phenotypic "ABO" blood groups are inherited antigenic substances which are found on the surface of red blood cells in addition to other tissues. ABO & Rhesus (Rh) blood groups systems besides being most important in blood transfusion also are important in disease susceptibility. The incidence of diabetes mellitus has been increasing and linked with many factors such as genetic, environment, diet, obesity, lack of exercise. The study envisages to further add to the existing knowledge on these factors. Material and Methods :Patients suffering from Type-2 Diabetes Mellitus (diagnosed by ADA criteria) admitted in medicine ward were selected for the study and enrolled as cases and almost equal no. of non diabetic subjects were taken as controls ( after taking informed consent) to compare distribution of ABO blood group. Detailed information about age, gender, BMI, age of onset of diabetes mellitus was noted. The records (clinical examination and investigations done by physician) were screened to find any complications. Determination of ABO and Rh status was done by standardslide method of agglutination. Results: No statistically significant difference was observed between cases and controls for different blood groups. The same findings were noticed when comparison was made between cases and controls for Rh typing. More than three fourth (76.19 %) cases with blood group B had developed one or the other complication as a sequel of the disease. Conclusion: Our study didnot show any difference between cases and controls for different blood groups and Rh factor. However statistical significant relationship of complications with B blood group is observed.
Authors and Affiliations
Dr. Geetika Gupta
Keywords
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