Association of complete blood count parameters with IgE levels and disease severity, atopy type in allergic rhinitis patients
Journal Title: Gulhane Medical Journal - Year 2020, Vol 62, Issue 3
Abstract
Aims: The aim of this study was to investigate the relationship between complete blood count (CBC) parameters and atopy type, disease severity, presence of concomitant conjunctivitis in patients with allergic rhinitis (AR). Methods: In this retrospective study, patients who presented to the immunology and allergic diseases outpatient clinic with rhinitis symptoms and who were found to have proven AR by allergy tests were included. CBC parameters and specific/total immunoglobulin E (IgE) analyses which were measured in the period of active disease were recorded. Results: Totally 242 patients met the enrollment criteria and were included in the study. AR patients with concomitant conjunctivitis had a significantly higher eosinophil count than patients without conjunctivitis (280.13±228.58/mm3 vs. 231.50±199.92/mm3, respectively, p=0.047). The presence of both concomitant pollen and mite atopy was significantly more frequent in the moderate/severe persistent group than in the other groups (p<0.001). Serum total IgE levels were significantly higher in group with patients who had both mite and pollen atopy than in the other groups (168.11±189.27, 149.69±178.21 and 368.53±430.31 IU/mL, respectively, p=0.005). The presence of conjunctivitis was significantly more frequent in patients with pollen atopy than in patients who did not have (46.9% vs. 30.3%, p=0.021). Conclusions: Although serum eosinophil count and total IgE levels are not sensitive enough in predicting the severity of AR patients, we believe that they can be helpful in diagnosis of patients with concomitant conjunctivitis and in presence of multiple aeroallergen sensitivity.
Authors and Affiliations
Ali Selçuk, Gürhan Taşkın
Keywords
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- EP ID EP688871
- DOI 10.4274/gulhane.galenos.2020.900
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