Association of eosinophils in Hashimoto’s thyroiditis on fine needle aspiration cytology
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 1
Abstract
Hashimoto’s thyroiditis (HT) is an autoimmune chronic inflammatory condition characterized by destruction of thyroid gland that may end up in a lifelong thyroxine supplementation. FNAC has a diagnostic accuracy of 90% in diagnosing HT, but has some inherent limitations. Therefore, we should search for some additional cytological findings which can improve the efficacy of FNAC in diagnosing HT. The aim was to study the association of eosinophils in Hashimoto’s thyroiditis on fine needle aspiration cytology. This was a case-control study, where 50 diagnosed cases each of HT and colloid goiter were served as cases and controls respectively. FNAC smears of diagnosed HT and colloid goiter cases were reviewed, number of eosinophils and neutrophils per high power field were counted and ratio of eosinophils to neutrophils were calculated and compared using unpaired t-test. In our study we observed higher eosinophil to neutrophil ratio in smears diagnosed as HT than colloid goiter. On applying the unpaired-t test, the P-value was <0.0001 with a 95% confidence interval, which was extremely significant statistically. Thus, there was a higher association of thyroid tissue eosinophilia with HT. Keywords: Eosinophils, Neutrophils, Hashimoto’s thyroiditis, Colloid Goiter, fine-needle aspiration cytology
Authors and Affiliations
Dr. Navya. B. N, Dr. Meenu. E. V, Prof. T. M. Kariappa
Keywords
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