ASSOCIATION OF GAMMA GLUTAMYL TRANSFERASE AND BLOOD LIPID LEVELS IN TYPE 2 DIABETIC SUBJECTS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 8
Abstract
Objective: The present study analyzed the correlation of ϒ-glutamyl transferase (GGT) with the high density lipoprotein and low density lipoprotein in type 2 diabetics. Study Design: Case control study. Study setting & Duration: Department of Medicine- LUMHS Jamshoro, from January 2016 to September 2016. Subjects & Methods: 100 type 2 diabetics and 100 controls were selected through non-probability (purposive) sampling. Clinical history, physical examination and blood biochemical findings were noted in proforma. Biochemical tests were performed as per standard criteria on Roche Hitachi Chemistry Analyzer. GGT was detected by IFCC method. Data was analyzed at 95% confidence interval on the statistical package SPSS 22.0 (IBM, Incorporation, USA) and Microsoft excel. Results: The GGT was noted as 20.44±5.71 and 39.5± 5.56 U/L (P=0.0001) and the HDLc as 49.15±3.67 and 30.19± 10.61 U/L in controls and cases respectively (P=0.0001). GGT showed positive correlation with systolic BP, diastolic BP, blood glucose, HbA1c, creatinine, cholesterol, triglycerides and LDLc. Negative correlation was found of GGT with the HDLc (r= - 0.676, P=0.0001). Conclusion: The present study found negative correlation of GGT with HDLc but positive correlation with LDLc. Hence, the GGT may be exploited as a simple and inexpensive atherogenic biomarker instead of expensive lipid profile.
Authors and Affiliations
Dr. Poonam Bai
Keywords
Related Articles
- EP ID EP630679
- DOI -
- Views 138
- Downloads 0
POSSIBLE EXISTENCE OF A METAMATERIAL INSIDE MICROTUBULES AND THE RESULTING EXPLANATION FOR ANESTHETIC ACTION OF SUPERLUMINAL PHOTONS UPON CONSCIOUSNESS
D. Georgiev presented an idea that consciousness could be the result of quantum computation via short laser-like pulses controlling quantum gates within the brain cortex. However, he later rejected this theory because th...
GENETIC ANALYSIS
The human body is composed of diploid cells that carry identical DNA and haploid gametes (egg and sperm) that carry sex chromosome either X or Y. The human genome is composed of over 3 billion base pairs of information o...
A STUDY OF INITIAL NEUROLOGICAL SYMPTOMS AMONG BANGLADESHI MULTIPLE SCLEROSIS PATIENTS
This study was undertaken in the Department of Neurology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from January 2002 to December 2003. The objective of this study was to determine the initial neurologi...
CARDIOVASCULAR RISK FACTORS AMONG ADULTS IN THE UNITED ARAB EMIRATES.
Background: Cardiovascular disease (CVD) has emerged as a major cause of morbidity and mortality. Research on CVD risk factors is necessary to reduce or overcome the risk of cardiovascular disease incidence. The knowledg...
BIOSYNTHESIS AND CHEMICAL SYNTHESIS OF BILE ACIDS AND THEIR BIOMEDICAL APPLICATIONS
Bile acids are amphiphilic molecules consisting of a hydrophobic and a rigid steroid nucleus, which they are attached a hydrophilic hydroxyl groups and a flexible acidic aliphatic side chain. The steroidal core of bile a...