Association of HbA1c with Dyslipidemia in Diabetes Mellitus
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 7
Abstract
Abstract:Type-2 Diabetes Mellitus (T2DM) is a rising pandemic with the number of patients expanding rapidly in both developed and developing countries around the world. Diabetic patients with associated dyslipidemia are easy targets for cardiovascular diseases (CVD). This study was an attempt to determine lipid abnormalities associated with Type-2 Diabetes Mellitus and association between glycated hemoglobin (HbA1c) levels and serum lipid profile to assess the importance of HbA1c as an indicator of dyslipidemia and future risk of cardiovascular disease in our local population of Jodhpur city which is situated in the north west of India. In this cross-sectional study, 140 known patients of Type-2 Diabetes Mellitus within 40-70 years of age were randomly selected. They were investigated for HbA1c and lipid profile. The data obtained were analyzed by appropriate statistical methods. Amongst the experimental group, 64.3% patients showed poor glycemic control and the rest 35.7% with good glycemic control, acted as the control subjects. In the present study, dyslipidemia was observed in 70.16% patients of Type-2 Diabetes Mellitus. Of these, 16.8% had single abnormal lipid parameter while 53.36% had associated dyslipidemia. There was exceptionally critical relationship between HbA1c and total cholesterol (TC), HbA1c and low density lipoprotein cholesterol (LDL-C), HbA1c and triglycerides (TG), HbA1c and Tc/HDL proportion and HbA1c and non HDL-cholesterol. Likewise, exceedingly huge reverse connection between HbA1C and HDL cholesterol was established. Apart from dependable glycemic control, HbA1c can likewise be utilized as an indicator of dyslipidemia and in this way early diagnosis of dyslipidemia can be utilized as a preventive measure for the improvement of CVD in patients with T2DM. Keywords:Diabetes Mellitus, cardiovascular disease, dyslipidemia, glycated hemoglobin, lipid profile.
Authors and Affiliations
Aishwarya Purohit, Nitin Sharma, Aastha Gaur
Keywords
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