Association of helicobacter Pylori Infection and Vitamin B12 Level among Sudanese Patients

Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3

Abstract

Background:Helicobacter Pylori (H. Pylori) infection is a major gastric infection worldwide and has been associated with many hematologic disorders. Objective: The purpose of this study was to determine the association between H.Pylori infection and vitamin B12 levels among Sudanese population. Materials and Methods: 120 samples were collected for this study (60 samples fromH.Pylori positive patients and 60 samples from apparently healthy individuals as controls).All samples were assessed for hematological parameters and vitamin B12 using Electrochemiluminescence immune assay . Results:Vitamin B12 levels mean was significantly lower among H. Pylori patients (207.56±184.51) than controlgroup (494.45±181.47)(P-value0.000),lymphocyte count mean in H.Pylori positivepatients(37.33±9.53)was significantly higher than the controls (32.28±8.72)( P-value 0.003), Granulocyte count meanwas lower among H.Pylori positive Subjects(51.53±9.91) than control subjects(57.10±8.43) (P-value 0.001).Other hematological parameters showed no significant difference between H.Pylori positive patients and control subjects. Conclusion: This study has concluded that vitamin B12level is lower in H.Pylori infectedSudanese individuals.

Authors and Affiliations

Ahmed T. Humeida, Mahdi H. A. Abdalla

Keywords

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  • EP ID EP591259
  • DOI 10.9790/0853-1603011214
  • Views 78
  • Downloads 0

How To Cite

Ahmed T. Humeida, Mahdi H. A. Abdalla (2017). Association of helicobacter Pylori Infection and Vitamin B12 Level among Sudanese Patients. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS), 16(3), 12-14. https://europub.co.uk/articles/-A-591259