ASSOCIATION OF LIPID PROFILES WITH 10-YEAR ATHEROSCLEROTIC CARDIOVASCULAR DISEASE RISK: STUDY AMONG SUBJECTS IN SLEMAN DISTRICT OF YOGYAKARTA INDONESIA
Journal Title: Asian Journal of Pharamceutical and Clinical Research - Year 2017, Vol 10, Issue 12
Abstract
  Objectives: The subjects in the Sleman District of Yogyakarta had medium Framingham risk score (FRS) in the preceding year study. The 10-year atherosclerotic cardiovascular disease (ASCVD) risk was a newer risk estimator than FRS. This study aimed to associate the lipid profiles with the ASCVD risk.Methods: The study was conducted with a cross-sectional design and the subjects were selected with cluster random sampling. The association of lipid profiles and ASCVD risk was analyzed with Mann–Whitney/Kruskal–Wallis tests and Spearman’s rho correlation, whereas the categorical scores within sub-groups were analyzed Chi-square statistics, respectively.Results: The eligible subjects (n=221) had the age at 51.7±8.1 years, systolic/diastolic blood pressure 136.8±22.4/85.0±12.4 mmHg, total-cholesterol (total-C), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), and triglyceride at 202.0±34.9 mg/dl, 52.6±12.5 mg/dl, 126.3±30.0 mg/dl, and 135.9±95.4 mg/dl, respectively; with hypertension treatment 16.7%, smoking 52.9%, diabetes 10.4%, and the median ASCVD risk at 4.4 (0.2-41.4). The ASCVD risk has significant association with non-lipid profiles, total-C, lipid ratio of triglyceride/HDL-C, total-C/HDL-C, and LDL-C/HDL-C, to a lesser extent, HDL-C, LDL-C, and triglyceride.Conclusion: The 10-year ASCVD risk of the subjects was categorized as low and had a significant association with total-C and lipid ratio of triglyceride/ HDL-C, total-C/HDL-C, and LDL-C/HDL-C.
Authors and Affiliations
Rita Suhadi, Dita Maria Virginia, Christianus Heru Setiawan
Keywords
Related Articles
- EP ID EP605520
- DOI 10.22159/ajpcr.2017.v10i12.20675
- Views 84
- Downloads 0
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