Association of Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) with Acute Coronary Syndrome (ACS).

Abstract

Platelets play a key role in pathogenesis of Acute Coronary Syndrome (ACS). A careful study and identification of these risk factors is important for diagnostic and prognostic importance. Thus, the present study shows that platelet indices like Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) can act as reliable diagnostic indicators especially in patients with raised Troponin-T. MPV & PDW is a part of basic Complete Blood Count (CBC) provided by automated haematology analysis which are rarely used in clinical practice and correlation for acute coronary syndrome. High MPV has been associated to more reactive platelets and regarded as an independent risk factor for myocardial infarction. In this study 36 patients suffering from Acute Coronary Syndrome (ACS) with elevated Troponin-T were evaluated against 15 healthy individuals (control). The results obtained showed significantly higher MPV and PDW in these cases. The assessment of blood samples is done by Sysmex-SX 800i autoanalyzer. The p value for MPV and PDW is < 0.001. Hence a positive correlation can be made between raised MPV and PDW with raised Troponin-T levels.

Authors and Affiliations

Thatai Akanksha Anil

Keywords

Related Articles

Comparative Study between Non Descent Vaginal Hysterectomy and Abdominal Hysterectomy- A Prospective Study.

Introduction: Hysterectomy is the most common major gynaecological surgery. Can be done by abdominal or vaginal route or laparoscopically. Laparoscopically assisted vaginal hysterectomy (LAVH) is increasing,but is cost...

Enamel Hypoplasia Enhancing Esthetics with Direct Composite Veneering Using IPS Empress Direct - A Case Report

Enamel hypoplasia affects the hard tissues of the teeth. It occurs due to disturbances during the formation of the tooth. It often leads to unesthetic appearance due to pitting and yellowish or brownish appearance of the...

Clinical Study and Management of Mass in Right Iliac Fossa at M.G. Hospital Bhilwara Rajasthan

Background - A mass in the right iliac fossa is a common diagnostic problem. Methods- 100 patients with signs and symptoms of right iliac fossa mass admitted in Department of surgery, M.G.Hospital, Bhilwara, Rajasthan we...

Effectiveness of Mifipristone in the treatment of Uterine Leiomyoma

Aim: To evaluate the efficacy of oral mifepristone in decreasing the severity of symptoms and in decreasing uterine and fibroid volume. Methods: This was a prospective study conducted in the department of Obstetrics and...

The level of job satisfaction among doctors of General Duty Medical Officer (GDMO) Cadre with post graduate qualification of central health services (CHS) in a central government teaching hospital in Delhi.

In India major burden of delivering effective health services falls on the public sector. Currently in our country the public health system is resource limited and is under the pressure of high burden of disease. Healthc...

Download PDF file
  • EP ID EP522536
  • DOI -
  • Views 115
  • Downloads 0

How To Cite

Thatai Akanksha Anil (2018). Association of Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) with Acute Coronary Syndrome (ACS).. International Journal of Medical Science and Innovative Research (IJMSIR), 3(11), 206-210. https://europub.co.uk/articles/-A-522536