Association of Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) with Acute Coronary Syndrome (ACS).
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 11
Abstract
Platelets play a key role in pathogenesis of Acute Coronary Syndrome (ACS). A careful study and identification of these risk factors is important for diagnostic and prognostic importance. Thus, the present study shows that platelet indices like Mean Platelet Volume (MPV) and Platelet Distribution Width (PDW) can act as reliable diagnostic indicators especially in patients with raised Troponin-T. MPV & PDW is a part of basic Complete Blood Count (CBC) provided by automated haematology analysis which are rarely used in clinical practice and correlation for acute coronary syndrome. High MPV has been associated to more reactive platelets and regarded as an independent risk factor for myocardial infarction. In this study 36 patients suffering from Acute Coronary Syndrome (ACS) with elevated Troponin-T were evaluated against 15 healthy individuals (control). The results obtained showed significantly higher MPV and PDW in these cases. The assessment of blood samples is done by Sysmex-SX 800i autoanalyzer. The p value for MPV and PDW is < 0.001. Hence a positive correlation can be made between raised MPV and PDW with raised Troponin-T levels.
Authors and Affiliations
Thatai Akanksha Anil
Keywords
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