Association of MELD Score with Colonic Mucosal Changes on Colonoscopy among the Patients of Portal Hypertension
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 6
Abstract
Introduction: Portal hypertension causes hemodynamic and mucosal changes in the entire gastrointestinal (GI) tract upper as well lower GI tract. The portal hypertension related changes in the colon described as portal hypertensive colopathy (PHC), colonic varices, rectal varices, vascular ectasia in colon & rectum and hemorrhoids. So we planned this study to assess whether the presence of portal hypertension related colonic lesions correlates with severity of liver disease as indicated by MELD scores. Materials and Methods: This study was done over a period of one year. In this study, 100 patients of portal hypertension due to different etiologies were taken if they met the inclusion criteria. A hospital based study was conducted by using predesigned and pretested Performa for obtaining information regarding socio-demographic variables, history of life style risk factors and lab investigations including upper GI endoscopy and colonoscopy at endoscopy lab. Data was expressed as rates, ratios and percentages and compared using Chi-square test and P value < 0.05 was considered significant. Results: In the present study most of the patients (67%) were male and 33% were female. Mean age of study patient was 45.91±15.28 years. In present study 62% of the patients were had MLED score 11-18,16% had MLED score 19-26 , 12% had MLED score ≤10 and only 10% had MLED score >27. Conclusion: Patients with portal hypertension have significantly higher frequency of colonic lesions as severity of liver disease increases indicated by colonoscopy and MELD scores. So it can be concluded that lower GI manifestation of portal hypertension are clinically significant with MELD score.
Authors and Affiliations
Rajesh Prajapati, Gurdeep Kaur, Vipin Mathur, Jainendra Sharma, Ranjana Veerwal, Poonam Kajla
Keywords
Related Articles
- EP ID EP533383
- DOI 10.21276/ijmrp.2018.4.6.039
- Views 71
- Downloads 0
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