Association of Red Cell Distribution Width and Hba1c in Type-2 Diabetes Mellitus
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 8
Abstract
Background: Diabetes Mellitus is recognized as major cause of death and disability with public health burden worldwide. Prevalence of diabetes with impaired glucose regulation (IGT and/or IFG) is the highest in developing countries. Objective: To find out the association and contribution of Red Blood Distribution Width (RDW), CRP and Glycated Haemoglobin (HbA1C) with type-2 diabetes mellitus. Methods: It was laboratory based cross sectional study and conducted 80 subjects in the Department of Laboratory Medicine and Endocrinology, Bangobandhu Sheikh Mujib Medical University, Bangladesh. After the laboratory works, data were inputted and analyzed through SPSS 24 version. Results: The mean age of the respondents was 45.06±11.08 years. 35% patient belonged to age ≤40years and 11.3% was ≥60 years. Mean value of RBC (×1012/L) was 4.73±0.57, RDW-CV (%) 14.55±1.11, HbA1c (%) 8.54±2.08 and CRP (mg/L) was 5.98±5.85. Correlation between HbA1c (%) and RDW was strongly related (P=0.001) and (r=0.457). CRP with RDW was p=0.001 and r=0.512. Conclusion: RDW and CRP were strongly correlated with HbA1c in type2 diabetes mellitus. Increased RDW likely reflects the presence of pro-inflammatory cytokines and oxidative stress. So, CBC, CRP and HbA1c test are very valuable and effective tool for monitoring DM and follow up.
Authors and Affiliations
Dr. Nasrin Jahan, Dr. Abu Md. Ahsan Firoz, Prof. Md. Farid Uddin, Prof. A. N. Nashimuddin Ahmed, Prof. Tuhin Sultana, Dr. Debatosh Paul, Dr. Saiful Islam, Dr. Nazia Islam, Mesbah Uddin Ahmed, Prof. Dr. Md. Quddusur Rahman
Keywords
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- DOI 10.9790/0853-1708101721.
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