Association of Risk Factors in Gestational Diabetes Mellitus among Pregnant Mothers Attending at a Tertiary Care Hospital in Bangladesh
Journal Title: Journal of Bioinformatics And Diabetes - Year 2014, Vol 1, Issue 2
Abstract
Objective: To observe association of risk factors with gestational diabetes mellitus (GDM) in a tertiary care hospital of Bangladesh. Materials and Methods: Risk factors of GDM were evaluated in pregnant subjects (n=385; age: 26.4±4.9 yrs; body mass index, BMI: 25.3±4.3 kg/m2; mean ± SD) screened by 75 gram oral glucose tolerance test (OGTT) following WHO 1999 criterion irrespective of gestational age in the Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University (BSMMU). BMI, maternal age, parity, trimester and family history of diabetes were considered as risk factors. Plasma glucose was measured by glucose-oxidase method on the same day. Results: GDM and normal glucose tolerance (NGT) showed significant difference for age (28.2±4.9 vs. 25.3±4.6 yrs, p<0.001), BMI (26.7±4.4 vs. 24.4±3.9 kg/m2, p˂0.001), family history of DM (55.5% vs. 43.0%, p=0.017) and number of gravida (p=0.048). There was no significant difference of frequencies of GDM among various trimesters (39.4% vs. 42.5% vs. 38.2%; χ2=0.653, p=0.721). OGTT performed before 24 weeks revealed GDM in about 44% (88/202). Multiple regression revealed age (p<0.001), BMI (p=0.007) and family history of DM (p=0.048) as independent predictors for GDM. Conclusion: It is concluded that age of mother, increased BMI, family history of diabetes as well as multigravidae are important predictors for GDM.
Authors and Affiliations
Nusrat Sultana, M A Hasanat, Sharmin Jahan, Mashfiqul Hasan, Yasmin Aktar, Sandesh Panthi, M Atiqur-Rahman
Keywords
Related Articles
- EP ID EP425884
- DOI 10.14302/issn.2374-9431.jbd-16-939
- Views 132
- Downloads 0
Bioinformatic Resources for Diabetic Nephropathy
The number of individuals with diabetes is increasing worldwide and a large subset of those affected will develop diabetic nephropathy. Diabetic nephropathy is the leading cause of end-stage renal disease, has serious he...
Association of Risk Factors in Gestational Diabetes Mellitus among Pregnant Mothers Attending at a Tertiary Care Hospital in Bangladesh
Objective: To observe association of risk factors with gestational diabetes mellitus (GDM) in a tertiary care hospital of Bangladesh. Materials and Methods: Risk factors of GDM were evaluated in pregnant subjects (n=38...
What Do Primary Care Prediabetes Patients Need? A Baseline Assessment of Patients Engaging in A Technology-Enhanced Lifestyle Intervention.
Objective: This study assessed the baseline knowledge, perceptions, attitudes and behaviors of prediabetes patients in order to tailor a new technology-enhanced primary care-based lifestyle modification intervention. M...
Computational STAT4 rSNP Analysis, Transcriptional Factor Binding Sites and Disease
Purpose Signal Transducer and Activator of Transcription 4 (STAT4) is important for signaling by interleukins (IL-12 and IL-23) and type 1 interferons and has been found to have several simple nucleotide polymorphisms (S...
Development of a Model-Based Noninvasive Glucose Monitoring Device for Non-Insulin Dependent People
Continuous-time glucose monitoring (CGM) effectively improves glucose control, as oppose to infrequent glucose measurements (i.e. using Lancet Meters), by providing frequent blood glucose concentration (BGC) to better as...