Associations between Mycoplasma and Components of Immune Response in Women with Autoimmune Thyroiditis
Journal Title: Міжнародний ендокринологічний журнал - Year 2014, Vol 7, Issue 63
Abstract
There was investigated immunoglobulin G (IgG) to the mycoplasma (Mp) in the blood serum of women with autoimmune thyroiditis (AIT) of reproductive age and in postmenopausal periods. A control group consisted of women of similar periods without thyroid pathology. The presence of AIT was found not to be associated with increased IgG level to Mp and age factor in women. At the same time, the activity of mycoplasma infection in postmenopausal women increases both in women with AIT, and in the control group, but in women without thyroid pathology it occurs significantly more intensive (4.4-fold compared with women in reproductive period, and in AIT women — on 13.5 %). In women with AIT reliable associative links between IgG to MP and CD3, CD4, CD8, CD16 levels were not revealed. At the same time in a reproductive period there is a significant positive correlation with CD20 and negative one with CD95 (marker of Fas-mediated apoptosis), and in postmenopausal women — with a direct indicator of humoral immunity — antibodies to TG.
Authors and Affiliations
O. A. Honcharova
Keywords
Related Articles
- EP ID EP229554
- DOI -
- Views 68
- Downloads 0
The Findings of Epidemiological Studies on the Prevalence of Iodine Deficiency Disorders in the Khorezm Region of Republic of Uzbekistan
Despite the ongoing programs aimed at the liquidation of iodine deficiency in the Republic of Uzbekistan, a high prevalence of iodine deficiency disorders (IDD) is being observed. As a result of epidemiological studies i...
Primary Adrenal Insufficiency
.
Beware of Pesudohealers of Diabetes!
The article deals with pseudohealing, topical question of all medical specialities including endocrinology. Each physician knows negative consequences of pseudohealer’s actions for patients, however there are no particul...
An Autoimmune Overlap Syndrome in Diseases of the Thyroid Gland — Terra Incognita of Thyroidology
Quite frequent thyroid pathology is an autoimmune disease. However, along with common autoimmune thyroid diseases — Graves’ disease, autoimmune thyroiditis, in clinical practice there are autoimmune overlap syndromes, w...
Ways for Improvement of Medical Care Provision to the in Patients with Thyroid and Concomitant Pathology
In research it was established prevalence and nature of concomitant diseases in patients with different thyroid pathology, hospitalized in endocrinology in-patient departments, volume and character of carried out therapy...