ASYMPTOMATIC CHRONIC CARRIER - A POTENTIAL HAZARD TO BLOOD RECIPIENTS - BLOOD BANK-BASED STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2017, Vol 4, Issue 29
Abstract
BACKGROUND Blood transfusion is an effective mode of transmission of hepatitis C infection. Hepatitis C is an emerging infection in India, which was detected in 1989. US and Japan started screening for HCV in 1990, which was mandatory and in India in 2002. Despite testing of blood units, HCV infection is still a significant problem. HCV is transmitted through blood and its components. MATERIALS AND METHODS The present study was conducted to detect hepatitis C in blood donors (voluntary and replacement donors) for two years and screening done by ELISA (3rd generation UBIR, HCV EIA.4-0 kit). RESULTS Seroprevalence of anti-HCV in 14,727 donors was 0.33%. Coinfection with HCV was observed in 3 donors of HBsAg and 1 donor of HIV seropositivity. Large number of donors were from urban areas (66.66%) and seropositivity among them was 0.36% and from the rural areas (33.34%) with seropositivity of 0.15%. CONCLUSION In conclusion, the present study has established the prevalence of HCV antibody in healthy donors was 0.29% in our area (Davangere). This proves that compulsory screening for HCV lowers the incidence of Post Transfusion Hepatitis (PTH).
Authors and Affiliations
Rukmini Sudhakar, Suresh Hanagavadi, Chandrashekhar H. R
Keywords
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- EP ID EP217813
- DOI 10.18410/jebmh/2017/328
- Views 129
- Downloads 0
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