Asymptomatic Chronic Lymphocytic Leukemia – presenting as Gastric lymphoma – A Case Report with Review of Literature

Journal Title: International Journal of Medical and Health Sciences - Year 2012, Vol 1, Issue 3

Abstract

A 60 year old known diabetic male patient attends medical outpatient department for routine diabetic checkup. Clinical examination remains unremarkable. Diabetic status was also under control. Routine complete hemogram showed Total Leucocyte count (TLC) of 2.1 lakhs/cu.mm and Absolute Lymphocytosis of 10 x 109/L. Peripheral smear revealed more than 85% of atypical lymphocytes. Peripheral blood subjected for Flow cytometric analysis and Immunochemistry showed positivity to B cell markers. Patient was diagnosed as a case of asymptomatic chronic lymphocytic leukemia (CLL); Rai stage 0 and anti-leukemic management was initialized. After two weeks, patient presented with generalized gastrointestinal symptoms – diarrhea, vomitings, gastritis, colic etc. Clinical examination was once again uneventful and endoscopy was performed. There was no evident macroscopic lesion. Biopsy from slightly elevated mucosa showed similar cells as that of B-CLL. Thus, further management was planned and case was diagnosed as Extranodal gastric lymphoma with infiltration of B-CLL.We present here a rare case of Asymptomatic CLL presenting as Gastric lymphoma. This report accentuates the precedence of combined and cumulative approach of clinician and a pathologist in present case which led to early diagnosis and management of the patient.

Authors and Affiliations

B V Sai Prasad, P Krishna Prasanthi, Md K Faheem N, K Ramesh, E Sudhakar Reddy

Keywords

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  • EP ID EP39679
  • DOI -
  • Views 332
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How To Cite

B V Sai Prasad, P Krishna Prasanthi, Md K Faheem N, K Ramesh, E Sudhakar Reddy (2012). Asymptomatic Chronic Lymphocytic Leukemia – presenting as Gastric lymphoma – A Case Report with Review of Literature. International Journal of Medical and Health Sciences, 1(3), -. https://europub.co.uk/articles/-A-39679