ASYMPTOMATIC URINARY TRACT INFECTIONS IN HOMOZYGOUS SICKLE CELL PATIENTS IN TOGO
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 7
Abstract
Urinary tract infections can complicate the condition of sickle cell patients by kidney damage. This study was initiated to evaluate the prevalence of urinary tract infections bacteria carriage in sickle cell patients and to determine the antibiotics susceptibility profile of these bacteria. Homozygous sickle cell patients, "SS", in the steady state, followed at the “Centre Hospitalier Universitaire-Campus” (CHU-Campus) of Lomé, were recruited on the basis of precise criteria. For these patients, cytobacteriological examinations of urine (ECBU) were performed. In all, 129 sickle cell patients with "SS" phenotype aged between 3 and 52 years, mean age 18.33 ± 0.90 years were selected. The sex ratio M / F was 0.72. The prevalence of carriage of bacteria responsible for urinary tract infections was 9.30%, 12 subjects, 11 of which were female. Escherichia coli was the most isolated bacteria, accounting for 66.67% of the isolates. Furthermore 85.7% of E. coli strains were resistant to Sulfamethoxazole-Trimethoprim, 75% to Nalidixic Acid, Ticarcillin and Ticarcillin-Clavulanic Acid, 14.3% to Piperacillin-Tazobactam and 12.5% to Ertapenem. All E. coli strains were sensitive to Amikacin and Meropenem. The results of this study will contribute to better management of infections in sickle cell patients by screening for urinary tract infections and routine antibiotic susceptibility testing.
Authors and Affiliations
Christèle TCHOPBA NGUEPOU
Keywords
Related Articles
- EP ID EP673627
- DOI -
- Views 146
- Downloads 0
ADOLESCENTS ANGER: A REVIEW
Anger is one of our most powerful emotional reaction that affects the human body. It is described as an intense feeling in response to frustration, hurt, disappointment, or threatening. Adolescents with more disorders ex...
BENEFITS AND DRAWBACKS OF BULK-FILL DENTAL COMPOSITES: A SYSTEMATIC REVIEW
Introduction: Bulk-fill composites were recently introduced, the published literature about their physical and mechanical properties yield inconsistent or sometimes contradicting results. Therefore, in depth review of th...
ULTRASOUND PREVALENCE OF GALL STONES IN A CROSS-SECTION OF OBESE NIGERIAN PATIENTS
Background: Obesity is becoming a public health challenge even in developing countries where it was previously uncommon. This increase may be expected to influence the prevalence of obesity related comorbidities and diso...
A NEW MOLECULE OF WATER-SOLUBLE POLYSACCHARIDE ISOLATED FROM EUCALYPTUS GROWING IN LEBANON
Objectives: To study and compare the chemical structure characteristics of the polysaccharides extracted from leaves of Eucaluptus globulus with chemical structure of fucoidans extracted from Dictyopteris polypodioides b...
IMPACT OF UTERINE FIBROIDS ON THE EFFECTIVENESS OF ICSI IN WOMEN OF ADVANCED REPRODUCTIVE AGE
This publication presents the results of a study conducted among women of older reproductive age on the impact of uterine fibroids on the effectiveness of ICSI.