Atherogenic Dyslipidemia in Diabetic Nephropathy

Abstract

Background: Dyslipidemia plays an important role in progression of kidney disease in patients of diabetes mellitus and leads to cardiovascular complications. The present study aimed to asses atherogenic lipid profile in patients of diabetes mellitus and diabetic nephropathy. Aim: To evaluate atherogenic lipid profile in patients of diabetes mellitus and diabetic nephropathy. Settings and Designs: This cross sectional study was undertaken in the Department of Biochemistry and kidney Unit, Department of Medicine and Department of Nephrology of Government Medical College and super speciality hospital Nagpur, Maharashtra. Material and Method : Total cholesterol (TC), Triglycerides(TG), High density lipoprotein (HDL), low density lipoprotein (LDL), very low density lipoprotein (VLDL), atherogenic ratio i.e. TC/HDL, LDL/HDL, was assessed in diabetes mellitus (n=50), diabetic nephropathy (n=50) and healthy individuals (n=50).Mean of biochemical parameter were compared by performing repeated measures one way ANOVA(F-test) and Post hoc multiple comparison of mean of three groups by Bonferroni t-test. Results: Values of total cholesterol, triglyceride ,LDL-C and TC/HDL, LDL/HDL were significantly higher in diabetes mellitus with diabetic nephropathy and diabetes mellitus without diabetic nephropathy but values of HDL-C (p<0.001) were significantly lower in diabetes mellitus with diabetic nephropathy and diabetes mellitus without diabetic nephropathy as compared to controls. Conclusion: Atherogenic dyslipidemia was more pronounced in diabetic nephropathy as compared to diabetes mellitus.

Authors and Affiliations

Katore Sarika D , Mahajan Bhushan H. , Fating Prasanna M. , Muddeshwar Manohar G. , Pramanik Sanjay

Keywords

Related Articles

Phenylarsenic(III) Derivatives of Schiff Bases; Synthesis and Characterization

Complexes having the general formula Ph As [ OC (R) CHC(R') NC6H5]n CI2-n[ where n=1 or 2; R=R' =CH3, C6H5; R=CH3, R'=C6H5] have been synthesized by the reactions of phenyl arsenic(III) dichloride with the sodium salts o...

A study on awareness and attitude of organ donation among arts college students of Thiruvannamalai district, Tamil Nadu 2017

Background: There is an increasing discrepancy between the number of patients on the waiting list for organ transplantation and the available number of donors. Evaluation of college students’ awareness and attitude is of...

Perforated Peptic Ulcer Mimicking Strangulated Femoral Hernia – a Rare Presentation

Peptic ulcer perforation presents no difficulty in diagnosis when large quantity of gastric content floods the peritoneal cavity. Presentation is atypical and diagnosis is difficult when the stomach is either atypical in...

A study of clinical profile of community - acquired pneumonia in diabetes mellitus

Background: Community- acquired pneumonia may cause significant morbidity and mortality, especially in patients who have comorbidities. Diabetes mellitus is associated with increased susceptibility to infection due to it...

Download PDF file
  • EP ID EP110249
  • DOI -
  • Views 104
  • Downloads 0

How To Cite

Katore Sarika D, Mahajan Bhushan H. , Fating Prasanna M. , Muddeshwar Manohar G. , Pramanik Sanjay (2014). Atherogenic Dyslipidemia in Diabetic Nephropathy. INTERNATIONAL JOURNAL OF RECENT TRENDS IN SCIENCE AND TECHNOLOGY, 10(3), 472-475. https://europub.co.uk/articles/-A-110249