Attempts of activating carboxylic group of 3-amine-1-Hpyrazole-5-carboxylic acid using azide method
Journal Title: CHEMIK nauka-technika-rynek - Year 2014, Vol 68, Issue 4
Abstract
The method was developed for linking 3-acetamido-5-carboxy- 1H-pyrazole with protein amino acid from C-end without necessity to protect side functional groups of pyrazole ring by means of azide activation. In the model reaction N-(3-acetamido-5-carbonyl-1Hpyrazole) glycine methyl ester was synthesized.
Authors and Affiliations
A. Kusakiewicz-Dawid, E. Masiukiewicz
Keywords
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