Attenuation of pressor response to laryngoscopy and intubation: Dexmedetomidine Vs. fentanyl premedication
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 4
Abstract
Introduction The pressor response during laryngoscopy and intubation is part of a huge spectrum of stress response results from the increase in sympathetic and sympathoadrenal activity The present study was planned to observe the attenuation of pressor response during laryngoscopy and intubation with dexmedetomidine and fentanyl also to compare the effectiveness between these two drugsMaterials and Methods In this study we include 128 patients of ASA grade I II aged 18 65yrs of either gender scheduled for elective surgery under general anaesthesia Groups Group D Dexmedetomidine 06gkg and Group F Fentanyl 2gkg these drugs diluted with NS to make 10 ml given IV slow over 10 min Vital parameters HR SBP DBP and MBP were recorded as baseline then at 10 minutes after premedication and then at 12357 and 10 minutes after endotracheal intubationResults There was significant increase in heart rate systolic blood pressure and diastolic blood pressure during laryngoscopy and intubation in group F as compared to group D pConclusion Dexmedetomidine 06mcgkg is superior to fentanyl 2mcgkg in the attenuation of the pressor response and that the ideal time for its administration should be about 10 minutes before a laryngoscopy and intubation Keywords Dexmedetomidine Fentanyl Intubation Laryngoscopy Pressor response
Authors and Affiliations
Ravindra Kumar Gehlot, Lalit Kumar Raiger, Gokulakrishnan L, Madhan Chandramohan, Apoorva Aseri
Keywords
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- EP ID EP476481
- DOI 10.18231/2394-4994.2018.0093
- Views 94
- Downloads 0
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