Autoantibodies and Disability in Long-Standing Rheumatoid Arthritis
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 4
Abstract
Objective: This study analyzed RF and MCV relationship with HAQ score to predict disability in rheumatoid arthritis patient on DMARD therapy. Method: This study was conducted among 92 female patients with rheumatoid arthritis selected from different rheumatology OPD clinic; RF, MCV, ESR, CBC, STDWL, SDAI, HAQ Di self-reports, VAS scale, deformity and disease comorbidity were recorded in this study. Results: the results of this study showed, age 38.09±3.30 years, disease duration 6.45±1.17, rheumatoid factor 65.57±67.27, SDAI was 48.51± 25.02, STDL 26.15±13.30. HAQ-Di was 2.45±.1.17, anti-MCV 157.89±255.92, and VAS 5.92±2.65. There is a significant relation with MCV and positive correlation with extra-articular manifestation, Deformity and STDWLP<0.05. But, RF has a significant relation with STDWL, SDAI P<0.05. Otherwise, no significant relation was seen P>0.05. Functional disability HAQ, VAS, ACR CLASS) in the study group showed a significant relation with both RF and MCV; MCV more significantly than RF P<0.05 with a significant positive correlation between HAQ, VAS with MCV P<0.05 but, not with RF P>0.05. Conclusion: HAQ score is the simplest possible tool used to assess RA disease activity and highest was recorded was after 5th years duration of the disease activity in this study, but it should be recorded regularly during follow-up of the patient with RA to predict early future disability.
Authors and Affiliations
Sami Abdulahakim
Keywords
Related Articles
- EP ID EP285029
- DOI -
- Views 31
- Downloads 0
The Trends of Progesterone Hormone in Advancing Pregnancy of Human Immunodeficiency Virus-infected Women: A Cohort Study in Western Kenya
Despite many studies on Human Immunodeficiency Virus (HIV) and pregnancy, there is still insufficient information regarding the effect of HIV on progesterone in advancing pregnancy. In a prospective cohort study, 44 anti...
Effectiveness of Diclofenac Suppository in Post LSCS Patients for Immediate Post Operative Analgesia after Lumbar Subarachnoid Blockade
Background: Pre emptive analgesia following or before lumbar subarachnoid blockade can be instituted through several means. But use of diclofenac suppository is one of the easiest ways to administer in the parturient by...
Comparative Study of Pleural Fluid Culture in Standard Culture Bottle and Blood Culture Bottle for the Evaluation of Empyema
Background: Bacterial pleural infection has been a substantial clinical challenge since ancient times. Identification of the infecting bacteria by culture of pleural fluid is of great importance for clinical care. Inocul...
Cerebrovascular Accidents as a Cause of New Onset Seizure and Its Correlation with Age of Onset
INTRODUCTION: Seizure has been a recognized entity since antiquity and is probably as old as man himself. Seizures are common disorders found all over the world and are encountered frequently during medical practice in v...
Review of Graft Choices for Anterior Cruciate Ligament
The question of which graft to use for anterior cruciate ligament (ACL) reconstruction continues to be debated at meetings around the world. The overall choice of grafts consists of autografts, allografts, and synthetic...