Abstract

Castleman's Disease (CD) is a rare benign lymphoproliferative disorder of uncertain origin which most commonly involves the mediastinum but rarely affects the axilla. We report a case of voluminous axillary unicentral CD, detected due to palpation of a painless mass in the left axilla in a healthy 32-year-old woman. Ultrasound and Computed Tomography (CT) imaging revealed a 7 cm left axillary-supraclavicular lymph-node capsulated with no vascular stenosis. A needle biopsy was performed and a histological examination revealed typical hyaline-vascular type CD. A careful surgical excision was performed with uneventful postoperative course and was dismissed after five postoperative days. Six months later CT scan showed complete remission. Although primary axillary localization of CD is rare, it is a possible cause of peripheral lymphadenopathy. A complete surgical excision is mandatory.

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