Bacterial DNA Vaccines in Veterinary Medicine: a Review
Journal Title: Journal of Veterinary Advances - Year 2012, Vol 2, Issue 4
Abstract
Vaccines are one of the greatest achievements of modern medicine. Conventional vaccines have been used to control various infectious diseases for more than 200 years. However new vaccine strategies, which have great advantages over conventional vaccines in reliability, ease of production, stability and transportation, have been developed in parallel with the advances particularly in molecular biology, genetics, microbiology and immunology. One of these advances is the DNA-based vaccine development approach, and the studies on vaccines against various pathogens of primary importance in veterinary medicine are being pursued. DNA vaccination entails the administration of the DNA encoding vaccine antigen into the target organism (a recipient). DNA taken up by the host cell is then transcribed into mRNA, from which the vaccine proteins are translated. Host immune system recognizes the proteins expressed, and generates humoral (antibody)- and/or cell-mediated immune response. This review summarizes the current information on DNA vaccine studies against important bacterial pathogens in veterinary medicine.
Authors and Affiliations
Fındık A. and Çiftci A.
Keywords
Related Articles
- EP ID EP156386
- DOI -
- Views 94
- Downloads 0
Bacteriological Quality of Freshwater Fishes Caught from Sokoto River, Sokoto, Nigeria
The study was conducted to evaluate the bacteria quality of freshwater fishes caught from Sokoto River. A total of 90 fish samples comprising 18 samples each of 5 genera, were randomly procured over a period of 3 months....
Iron Nutrition and Anaemia in Piglets: a Review
Man has known that iron plays an important role in health and disease for considerable time (Loosli, 1978). Bryan (1931) stated that documented therapeutic use of iron date back as far as 1500BC. Iron was recognised as v...
Incidence of Aspergillus Section Flavi and concentration of aflatoxin in feed concentrates for Cattle in Jos, Nigeria
Samples of two types of cattle feed concentrates compounded at the feed mill section of the National Veterinary Research Institute (NVRI), Vom, Nigeria were evaluated for incidence of toxigenic Aspergillus section Flavi....
A Five Year Retrospective Study of Bovine Tuberculosis Granulomatous Lesions in Slaughtered Cattle in Adamawa State, Nigeria
A five-year (2008 – 2012) retrospective study was carried out in 10 Local Government Areas (LGAs) of Adamawa State to determine the prevalence of bovine tuberculosis (BTB). Slaughter Slab records of tuberculosis suspecte...
The Use of Ethnoveterinary Medicine in Goats in Lentsweletau Village in Kweneng District of Botswana
The study was conducted to document the use of ethnoveterinary medicine in goats in Lentsweletau village in Kweneng district of Botswana. Structured questionnaires were used to collect information from 30 goat owners. Th...