Bacterial etiology and antibiotic susceptibility pattern of female patients with urinary tract infection referred to Imam Khomeini Hospital, Ahvaz, Iran, 2019

Journal Title: Journal of Current Biomedical Reports - Year 2020, Vol 1, Issue 1

Abstract

Urinary tract infection (UTI) is one of the most frequent infections among women, and if untreated could lead to severe complications. The treatment of UTI is difficult due to the appearance of pathogens with increasing resistance to antimicrobial agents. This study thus aimed to determine the bacterial etiological pathogens of UTI and the antibiotic sensitivity pattern of the pathogens isolated. This descriptive cross-sectional study was performed from March to September 2019 on a total of 339 women referred to Imam Khomeini Teaching Hospital in Ahvaz, Iran. Mid-stream urine samples were collected from the patients and were cultured. The presence of significant bacteriuria (> 105 CFU/mL) was determined using the plate count method. The antimicrobial susceptibility test was done by the standard disk diffusion method. The most frequently isolated pathogens were Escherichia coli (54.8%), Klebsiella (18.2%), Pseudomonas aeruginosa (9.9%), Proteus (8%), and Acinetobacter (5.1%). E. coli, as the most common pathogen of UTIs, showed the most resistance to cephalosporins and the least resistance to imipenem. According to the findings, E. coli was the most common cause of UTI in our region. Considering the rate of UTI, and the importance of preventing its severe complications, a survey of regional resistance patterns and timely treatment can control the development of its resistant bacteria.

Authors and Affiliations

Sousan Akrami, Reza Abouali, Mohammad Mostafa Olapour, Rozhin Heidary Lal Abady, Hamid Yazdaninejad, Arshid Yousefi Avarvand

Keywords

Urinary tract infection; Antibiotic resistance; Uropathogens

HIV/AIDS awareness and attitude among factory workers in Shiraz, Iran

HIV has been introduced as a causative agent for AIDS which is still considered as a major health problem for the country and a burden on the health care system. Raising awareness and knowledge plays a critical role in c...

The role of proteases in the invasion of SARS-CoV-2 virus into human host cells

The new coronavirus, which originally broke out in Wuhan, China, in December 2019, increase quickly around the world, causing a pandemic all over the world. The virus uses its spike protein to enter the human host cells....

The role of metalloproteinase and hypoxia conditions in endometrial cells and embryo implantation

In the process of implantation, metalloproteinase enzymes play a key role in basement membrane degradation and endometrial extracellular matrix. The activity of these enzymes is impeded by binding Tissue Inhibitors of Me...

Current applications of the microbiome engineering and its future: A brief review

In the human body there are many microorganisms with a variable genetic content. These microorganisms play an important role in the metabolism, homeostasis, immune system and generally human health. Over the millions of...

Identification of bacterial isolates from nasolacrimal duct infection in children with congenital nasolacrimal duct obstruction from Feiz teaching hospital, Isfahan

Dacryocystitis is a lacrimal sac and duct inflammation. It can be inherited or congenital. Two primary forms are acquired dacryocystitis, acute and chronic. The goal of this study is to recognize common bacteria causing...