Bacterial Survey of Diabetic Ulcers in Diabetic Patients in Hospitals at Aba, Nigeria
Journal Title: Biomedical Journal of Scientific & Technical Research (BJSTR) - Year 2019, Vol 19, Issue 1
Abstract
Diabetic ulcers are usually seen as infected ulcers and run a chronic course. Selected documented records of diabetic patients with diabetic ulcers were taken from the laboratory sections of different hospitals and clinics in Aba. From these records, a total of 110 diabetic ulcer cases were used in this study irrespective of their sexes and ages. Trauma related ulcers were ruled out. Microscopy and culture of specimen or wound swabs from these ulcers after 48 hours at 360C incubation showed that the most common bacteria in these ulcers is Escherichia Coli (E.coli) followed by staphylococcus species which is 22%. These bacteria species were seen in most of these ulcers. This study showed that most diabetic ulcers are mostly or commonly infected by Escherichia species and staphylococcus species. Diabetes mellitus is one of the commonest diseases in tropical areas. Diabetes mellitus may be described as a syndrome characterized by hyperglycemia and disturbance of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action or both [1]. Aside complications like diabetic nephropathy, neuropathy and retinopathy, diabetic ulcers are seen as the most troubling problem in the hospitals and clinics [2]. Most times, it involves the attention of both surgeon and internal physicians. It has been reported that diabetic complications are associated with overproduction of Reactive Oxygen Species (ROS) [3]. This complication is considered the leading cause of death among these patients. Oxidation plays a major role in diabetes [4]. The increase in free radical release accompanied by decrease in antioxidants is a major cause of diabetes [5]. In diabetes mellitus, there are usually alterations in the endogenous free radical scavenging defenses which leads to ineffective scavenging of reactive oxygen species resulting to oxidative damage [6].
Authors and Affiliations
Akunneh Wariso C, Aduema W
Keywords
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- EP ID EP622747
- DOI 10.26717/BJSTR.2019.19.003236
- Views 171
- Downloads 0
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