Bacteriological profile and antimicrobial resistance of blood culture isolates among paediatric patients from tertiary care hospital
Journal Title: Journal of International Medicine and Dentistry - Year 2016, Vol 3, Issue 2
Abstract
Bloodstream infection ranges from self limiting infection to life threatening sepsis and requires rapid and aggressive antimicrobial treatment. A total of 928 blood samples were collected from suspected cases from August 2014 to July 2015, they were processed aerobically and antibiogram pattern was studied . Cultures were positive in 252 (27.16%) cases. All the positive cultures were obtained after 48 hours of incubation. Gram negative bacteria were 84(36.20%) of the total isolates and Gram positive were 108 (46.55%), Candida species were isolated in 40(17.24%) of cases. In gram negative isolates, highest resistance was seen for Ticarcillin- Clavulanic acid 22 (39.29%), Cefoperazone –sulbactum 22 (39.29%), Cefuroxime 22 (39.29%), Cefazolin 22 (39.29%) and Amoxicillin- Clavulanic acid 22 (39.29%); in contrast gram positive isolates showed resistance to Ciprofloxacin 40(100%). Blood cultures provide a valuable guide in identifying etiological agent and selecting appropriate antibiotic. This helps to achieve a high level antibiotic activity against the offending bacterial organism.
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