Bacteriological Profile and Antimicrobial Resistance Pattern of Bloodstream Infections in A Tertiary Care Hospital Set Up
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 4
Abstract
Bloodstream infections (BSIs) are one of the common causes of infective morbidity and mortality. Early detection of causative pathogens and their antimicrobial resistance helps to start the appropriate antimicrobial therapy thereby reducing the number of complications. The present study was conducted to determine the bacteriological profile of bloodstream infections and their antibiotic resistance pattern in our tertiary care setup. Blood samples were received in the department of Microbiology, Hind institute of medical sciences, Barabanki. The sample processing and identification was done as per the standard protocol. Antibiotic sensitivity testing was done using Kirby Bauer disk diffusion method as per Clinical Laboratory Standard Institute (CLSI) guidelines. A total of 521 samples were processed, out of which 174(33.4%) isolates were positive for bacterial growth. From 174 bacterial culture positive isolates, 62% gram positive and 38% gram negative bacteria were isolated respectively. The most common bacteria isolated was Coagulase negative Staphylococcus spp (CoNS) (33%) followed by Staphylococcus aureus(25%), Escherichia coli(10%) and Acinetobacter spp. (10%). All gram positive cocci were completely sensitive to linezolid and teichoplanin. The present study observed high prevalence of antimicrobial resistance both in gram positive and gram negative bacteria. Hence, it is important to know the current trend of antimicrobials and formulate the antibiotic policy in the hospital so that the clinicians can start the proper empirical treatment and prevent the injudicious use of antibiotics.
Authors and Affiliations
Anjali Agarwal, Sangram Singh Patel, Arti Negi, Sneha Mohan, Seema Bose
Keywords
Related Articles
- EP ID EP485359
- DOI -
- Views 74
- Downloads 0
Correlation of Clinical, Serological and Radiological Features of Severe Dengue Fever
Dengue virus can produce a wide spectrum of illnesses which include Dengue Fever (DF), Dengue Haemorrhagic Fever (DHF) and Dengue Shock Syndrome (DSS).This study is a retrospective analysis of various clinical manifestat...
Investigation of Blister Beetle (Lytta vesicatoria) Dermatitis Outbreak and Containment at Kwara State University Students’ Hostels
The study was undertaken to ascertain the causative agent and diagnosis of the clinical profile of patients that made them susceptible to Blister Beetle Dermatitis, efforts were also devoted to investigate risk factors a...
To Study and type the Ovarian Tumors based on Histopathological features
Abstract: Ovary is the most important organ, as it is concerned with the reproduction of progeny. Ovary is also unique in the variety of lesions that can arise from it. Ovarian cancer accounts for about 3% of all cancers...
Recto-Neovaginal Fistula Following Vaginoplasty for Vaginal Agenesis: Our Experience and Management Guidelines
Recto-neovaginal fistula is an abnormal communication formed between the rectum and newly formed vagina, following vaginoplasty for vaginal agenesis. It results in soiling of neovagina by fecal matter and inflicts great...
Cost-Effective Analysis of Generic versus Branded Oral Hypoglycaemic Agents in Patients with Type 2 Diabetes Mellitus- A Prospective Observational Study
Diabetes is a disproportionately expensive disease which requires a lifelong medical treatment. Many patients cut back on medication use because of cost pressures. It is claimed that the cost of generic medicines having...