Bacteriological Profile in Chronic Osteomyelitis Patientsand TheirAntibiogram in A Tertiary Care Hospital, Jamnagar, Gujarat, India
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Introduction: Chronic Osteomyelitis has been continuing as the most important cause of morbidity among patients with bone infections. Even though early detection of cases and advanced treatments are in process, osteomyelitis is still continued as a major problem due to treatment failures and multidrug resistance. This study was conducted to determine the pus culture of chronic osteomyelitis and their susceptibility pattern to variousantimicrobial drugs. Aim: 1)To isolate and identify the Aerobic bacteria causing chronic osteomyelitis in one hundred fifty patients attending Orthopaedic outpatient department and those admitted in Orthopaedic wards of Shri M.P. Shah Government Medical College, Jamnagar. 2)To study the antibiotic sensitivity of the bacteria isolated. Materials and methods: 150 pus samples taken aseptically were cultured on Blood and MacConkey agar plates aerobically at 37oC for 18-24 hrs. Culture isolates were identified by a series of standard biochemical reactions. Antimicrobial susceptibility testing was done by Modified Kirby-Bauer’s disc diffusion method and the results were interpreted following CLSI guidelines. Results: Study group comprised 108 males and 42 females. Majority of the patients were in the age group of 20 – 70 years 117 (78%) with trauma being the most common 76 (50.67%) predisposing factor. The commonest organisms isolated wereStaphylococcus aureus60 (60.60%) and Pseudomonas aeruginosa13 (13.13%). Majority of Gram positive organisms were sensitive to Linezolid and Vancomycin and Gram negative organisms to piperacillin tazobactam combination and ceftazidime. Conclusion: The wide range of causative organisms and degree of resistance to commonly used antimicrobials supports the importance of pus culture and provides important information to guide clinician’s choice of empirical antibiotics.
Authors and Affiliations
Ruchi V. Shah, Romin V. Sanghavi
Keywords
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- EP ID EP243646
- DOI 10.9790/0853-1610054750
- Views 93
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